QuickView for GDI1 (gene)

Gene Symbol:

GDI1 Homo sapiens

Full name:

GDP dissociation inhibitor 1

Synonyms:

1A, GDIL, MRX41, MRX48, OPHN2, RABGD1A, RABGDIA, XAP-4, rab GDP dissociation inhibitor alpha, GDI-1, guanosine diphosphate dissociation inhibitor 1, mental retardation, X-linked 48, oligophrenin-2, protein XAP-4, rab GDI alpha, rab GDP-dissociation inhibitor, alpha, testis secretory sperm-binding protein Li 208a

Genomic Location:

Chr X: 153318715-153325008

Description:

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rab...

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GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific cognitive disability.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

OCT1_07 ,  OCT1_04 ,  EVI1_04 ,  LYF1_01 ,  TTGGAGA_MIR5155P_MIR519E ,  TTGGGAG_MIR150 ,  PXR_Q2 ,  TST1_01 ,  POU3F2_02 ,  WGGAATGY_TEF1_Q6 ,  PIT1_Q6 ,  IK2_01 ,  IRF7_01 ,  KTGGYRSGAA_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-150 ,  Predicted Gene Targets for miR-218

Cytogenetic Map:

Xq28

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