QuickView for GJA3;jsessionid=CD5EC3467C74A52F9ABF43FB9D909FE2 (gene)
- Gene Symbol:
- GJA3
Homo sapiens - Full name:
- gap junction protein alpha 3
- Synonyms:
- CTRCT14, CX46, CZP3, gap junction alpha-3 protein, connexin-46, gap junction alpha 3, gap junction protein, alpha 3, 46kDa
- Genomic Location:
- Chr 13: 19610394-19633183
- Description:
-
The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3).
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
13q12.11
GO Molecular Function
passive transmembrane transporter activity | transmembrane transporter activity | gap junction channel activity | transporter activity | wide pore channel activity | channel activity
GO Biological Process
establishment of localization | cellular process | localization | passive transmembrane transporter activity | transmembrane transporter activity | gap junction channel activity | cell-cell signaling | nervous system process | cell communication | wide pore channel activity | visual perception | sensory perception of light stimulus | sensory perception | transmembrane transport | signaling | channel activity | multicellular organismal process
GO Cellular Component
integral component of membrane | cell | plasma membrane protein complex | intrinsic component of membrane | cell-cell junction | protein-containing complex | connexin complex | plasma membrane | gap junction | cell periphery | cell junction | membrane
