QuickView for GK;jsessionid=6CEE63BB7CD431447361AF7E5019CB3D (gene)
- Gene Symbol:
- GK
Homo sapiens - Full name:
- glycerol kinase
- Synonyms:
- GK1, GKD, glycerol kinase, ATP:glycerol 3-phosphotransferase, glycerokinase
- Genomic Location:
- Chr X: 30581461-30658646
- Description:
-
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcrip...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
Xp21.2
GO Molecular Function
ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | glycerol kinase activity | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
polyol metabolic process | cellular process | organic substance catabolic process | triglyceride metabolic process | carbohydrate catabolic process | catabolic process | cellular lipid metabolic process | glycerol metabolic process | alcohol metabolic process | carbohydrate derivative biosynthetic process | cellular biosynthetic process | organic hydroxy compound metabolic process | alcohol catabolic process | phosphorus metabolic process | lipid metabolic process | organophosphate metabolic process | small molecule metabolic process | cellular carbohydrate metabolic process | cellular carbohydrate catabolic process | glycerol-3-phosphate metabolic process | biosynthetic process | phosphorylation | lipid biosynthetic process | carbohydrate metabolic process | phosphate-containing compound metabolic process | glycerol kinase activity | glycerolipid metabolic process | neutral lipid metabolic process | metabolic process | organic substance metabolic process | glycerol-3-phosphate biosynthetic process | kinase activity | carbohydrate derivative metabolic process | cellular metabolic process | triglyceride biosynthetic process | acylglycerol metabolic process | glycerol catabolic process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | organelle outer membrane | cytoplasm | intracellular organelle | vesicle | extracellular exosome | mitochondrion | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | mitochondrial outer membrane | mitochondrial envelope | extracellular space | outer membrane | mitochondrial membrane | cytosol | intracellular | membrane
