QuickView for GLAST (gene)

Gene Symbol:

SLC1A3 Homo sapiens

Full name:

solute carrier family 1 member 3

Synonyms:

EA6, EAAT1, GLAST, GLAST1, excitatory amino acid transporter 1, GLAST-1, sodium-dependent glutamate/aspartate transporter 1, solute carrier family 1 (glial high affinity glutamate transporter), member 3

Genomic Location:

Chr 5: 36642446-36724191

Description:

This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.

This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

P53_DECAMER_Q2 ,  CCAGGTT_MIR490 ,  TTTGTAG_MIR520D ,  COMP1_01 ,  CTTTGTA_MIR524 ,  WTGAAAT_UNKNOWN ,  CDP_02 ,  TCTGATA_MIR361 ,  P53_02 ,  CTTTAAR_UNKNOWN ,  GGCAGCT_MIR22 ,  AACTTT_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-22 ,  Predicted Gene Targets for miR-361 ,  Predicted Gene Targets for miR-490

Cytogenetic Map:

5p13.2

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