QuickView for GNB1 (gene)

Gene Symbol:

GNB1 Homo sapiens

Full name:

G protein subunit beta 1

Synonyms:

MRD42, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, beta subunit, signal-transducing proteins GS/GI, guanine nucleotide binding protein (G protein), beta polypeptide 1, testicular tissue protein Li 72, transducin beta chain 1

Genomic Location:

Chr 1: 1706589-1812355

Description:

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of ce...

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Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_01 ,  YRTCANNRCGC_UNKNOWN ,  ZF5_01 ,  GCAAGGA_MIR502 ,  GTACTGT_MIR101 ,  NFKAPPAB_01 ,  ATGTACA_MIR493 ,  TGTATGA_MIR4853P ,  GTGACGY_E4F1_Q6 ,  ATAACCT_MIR154 ,  E2F_Q2 ,  NFKB_Q6_01 ,  AACTTT_UNKNOWN ,  ETF_Q6 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-324-5p ,  Predicted Gene Targets for miR-542-3p ,  Predicted Gene Targets for miR-485-3p ,  Predicted Gene Targets for miR-493-5p

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Cytogenetic Map:

1p36.33

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