QuickView for GPC6;jsessionid=7D29A8820CE63C1EE5AFBA827D143A08 (gene)

Gene Symbol:

GPC6 Homo sapiens

Full name:

glypican 6

Synonyms:

OMIMD1, glypican-6, glypican proteoglycan 6

Genomic Location:

Chr 13: 92677096-93853948

Description:

The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Mutations in t...

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The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Mutations in this gene are associated with omodysplasia 1.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AAANWWTGC_UNKNOWN ,  TATAAA_TATA_01 ,  DBP_Q6 ,  GTGACGY_E4F1_Q6 ,  ATGCTGC_MIR103_MIR107 ,  GGGCGGR_SP1_Q6 ,  PTF1BETA_Q6 ,  TCTATGA_MIR376A_MIR376B ,  MTF1_Q4 ,  GATA4_Q3 ,  ACAWNRNSRCGG_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  MZF1_02 ,  TAXCREB_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-431 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-376

Cytogenetic Map:

13q31.3-q32.1

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