QuickView for GPCR41 (gene)

Gene Symbol:

SLC52A2 Homo sapiens

Full name:

solute carrier family 52 member 2

Synonyms:

BVVLS2, D15Ertd747e, GPCR41, GPR172A, PAR1, RFT3, RFVT2, hRFT3, solute carrier family 52, riboflavin transporter, member 2, G protein-coupled receptor 172A, PERV-A receptor 1, porcine endogenous retrovirus A receptor 1, putative G-protein coupled receptor GPCR41, riboflavin transporter 3, solute carrier family 52 (riboflavin transporter), member 2

Genomic Location:

Chr 8: 145553033-145555753

Description:

This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as ...

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This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.

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Orthologs:

Macaca mulatta ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACACTCC_MIR122A

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-122a

Cytogenetic Map:

8q24.3

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