QuickView for GPX5 (gene)

Gene Symbol:

GPX5 Homo sapiens

Full name:

glutathione peroxidase 5

Synonyms:

HEL-S-75p, epididymal secretory glutathione peroxidase, EGLP, GPx-5, GSHPx-5, epididymal androgen-related protein, epididymis secretory sperm binding protein Li 75p, epididymis-specific glutathione peroxidase-like protein

Genomic Location:

Chr 6: 28601768-28609923

Description:

This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike several other characterized glutathione peroxidases, this enzyme is not a selenoprotein, lacking the selenocysteine residue. Thus, it is selenium-independent, and has been...

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This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike several other characterized glutathione peroxidases, this enzyme is not a selenoprotein, lacking the selenocysteine residue. Thus, it is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_04

Cytogenetic Map:

6p22.1

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