QuickView for GRIA1;jsessionid=310B31E86A19C5AA1CF091548DD72B9A (gene)

Gene Symbol:

GRIA1 Homo sapiens

Full name:

glutamate ionotropic receptor AMPA type subunit 1

Synonyms:

GLUH1, GLUR1, GLURA, GluA1, HBGR1, glutamate receptor 1, AMPA 1, AMPA-selective glutamate receptor 1, gluR-1, gluR-A, gluR-K1, glutamate receptor, ionotropic, AMPA 1

Genomic Location:

Chr 5: 152850499-153171354

Description:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classifica...

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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  AP1_C ,  TGIF_01 ,  STAT4_01 ,  TGANTCA_AP1_C ,  STAT1_02 ,  RYTTCCTG_ETS2_B ,  HOXA4_Q2 ,  SREBP1_Q6 ,  STAT1_03 ,  RFX1_01 ,  GGGAGGRR_MAZ_Q6 ,  AP1_Q6_01 ,  PAX4_02 ,  GGGYGTGNY_UNKNOWN ,  CAGGTG_E12_Q6 ,  E47_02 ,  BACH2_01 ,  CTTTAAR_UNKNOWN ,  GCM_Q2 ,  RORA1_01 ,  EN1_01 ,  BACH1_01 ,  TTGTTT_FOXO4_01 ,  RTTTNNNYTGGM_UNKNOWN ,  STAT5A_04 ,  PAX_Q6 ,  GTGGGTGK_UNKNOWN ,  RORA2_01 ,  TGACAGNY_MEIS1_01 ,  CTTTGT_LEF1_Q2 ,  AP1_Q4_01 ,  CTGRYYYNATT_UNKNOWN ,  TCF11_01

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Cytogenetic Map:

5q33.2

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