QuickView for GRIA3 (gene)

Gene Symbol:

GRIA3 Homo sapiens

Full name:

glutamate ionotropic receptor AMPA type subunit 3

Synonyms:

GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94, glutamate receptor 3, AMPA-selective glutamate receptor 3, dJ1171F9.1, gluR-3, glutamate receptor C, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3, glutamate receptor, ionotropic, AMPA 3

Genomic Location:

Chr X: 122145777-122452447

Description:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on t...

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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  PR_Q2 ,  GATTGGY_NFY_Q6_01 ,  PAX4_04 ,  OCT1_05 ,  ATF6_01 ,  OCT_Q6 ,  SYATTGTG_UNKNOWN ,  YTATTTTNR_MEF2_02 ,  EVI1_04 ,  YATTNATC_UNKNOWN ,  VDR_Q6 ,  XBP1_01 ,  STAT6_01 ,  CTTTGA_LEF1_Q2 ,  OCT1_Q5_01 ,  OCT_C ,  WHN_B ,  TAAWWATAG_RSRFC4_Q2 ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  COMP1_01 ,  ATAGGAA_MIR202 ,  GGGAGGRR_MAZ_Q6 ,  AR_Q6 ,  OCT1_Q6 ,  CDP_02 ,  TGCAAAC_MIR452 ,  ALPHACP1_01 ,  PXR_Q2 ,  TGCGCANK_UNKNOWN ,  HNF4_Q6 ,  TGCCTTA_MIR124A ,  CCAWYNNGAAR_UNKNOWN ,  STAT5A_03 ,  IRF_Q6 ,  CTTTAAR_UNKNOWN ,  YCATTAA_UNKNOWN ,  MYB_Q6 ,  GTGCCTT_MIR506 ,  MEIS1AHOXA9_01 ,  CAAGGAT_MIR362 ,  WTTGKCTG_UNKNOWN ,  CTGAGCC_MIR24 ,  CTGCAGY_UNKNOWN ,  TGCTTTG_MIR330 ,  TGATTTRY_GFI1_01 ,  CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  PAX4_03 ,  TCF1P_Q6 ,  CAATGCA_MIR33 ,  HTF_01 ,  GGGTGGRR_PAX4_03

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Cytogenetic Map:

Xq25

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