Correlation Engine 2.0
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QuickView for GRK3;jsessionid=C334B788719D2D1F44904F62090B5B24 (gene)

Gene Symbol:
GRK3 Homo sapiens Homo sapiens
Full name:
G protein-coupled receptor kinase 3
ADRBK2, BARK2, beta-adrenergic receptor kinase 2, adrenergic, beta, receptor kinase 2, beta-ARK-2
Genomic Location:
Chr 22: 24290861-24455259
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data sugg...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 22

GO Molecular Function

ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | G-protein coupled receptor kinase activity | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | beta-adrenergic receptor kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

establishment of localization | cellular process | localization | regulation of cellular process | response to stimulus | protein serine/threonine kinase activity | G-protein coupled receptor signaling pathway | protein modification process | macromolecule modification | G-protein coupled receptor kinase activity | nitrogen compound metabolic process | phosphorus metabolic process | vesicle-mediated transport | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | receptor internalization | protein metabolic process | beta-adrenergic receptor kinase activity | import into cell | metabolic process | endocytosis | protein kinase activity | organic substance metabolic process | signaling | cellular protein metabolic process | receptor-mediated endocytosis | kinase activity | cellular protein modification process | receptor metabolic process | cellular metabolic process | signal transduction | macromolecule metabolic process

GO Cellular Component

cell | cytoplasm | plasma membrane | cell periphery | cytosol | intracellular | membrane