QuickView for GSTP1 (gene)

Gene Symbol:

GSTP1 Homo sapiens

Full name:

glutathione S-transferase pi 1

Synonyms:

DFN7, FAEES3, GST3, GSTP, HEL-S-22, PI, glutathione S-transferase P, GST class-pi, GSTP1-1, deafness, X-linked 7, epididymis secretory protein Li 22, fatty acid ethyl ester synthase III

Genomic Location:

Chr 11: 67107862-67110699

Description:

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and t...

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Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

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Orthologs:

Mus musculus ,  C. elegans ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  TGANNYRGCA_TCF11MAFG_01 ,  NFE2_01 ,  AP1_01 ,  GGGCGGR_SP1_Q6 ,  WWTAAGGC_UNKNOWN ,  TGASTMAGC_NFE2_01

Cytogenetic Map:

11q13.2

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