QuickView for GUCA2B;jsessionid=506753D54F80E5E4B09BFCB87441E01B (gene)

Gene Symbol:

GUCA2B Homo sapiens

Full name:

guanylate cyclase activator 2B

Synonyms:

GCAP-II, UGN, guanylate cyclase activator 2B, prepro-uroguanylin, uroguanylin

Genomic Location:

Chr 1: 42391679-42394082

Description:

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and wat...

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This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF1_01 ,  HNF1_C ,  SREBP1_Q6 ,  MYB_Q5_01 ,  SREBP_Q3 ,  PAX4_03 ,  HNF1_Q6 ,  RYTAAWNNNTGAY_UNKNOWN ,  CP2_01 ,  GGGTGGRR_PAX4_03

Cytogenetic Map:

1p34.2

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