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QuickView for Gal-9 (gene)


Gene Symbol:
LGALS9 Homo sapiens Homo sapiens
Full name:
galectin 9
Synonyms:
HUAT, LGALS9A, galectin-9, ecalectin, gal-9, lectin, galactoside-binding, soluble, 9, tumor antigen HOM-HD-21, urate transporter/channel protein
Genomic Location:
Chr 17: 22982301-23000713
Description:
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a ...
Orthologs:
Mus musculus Rattus norvegicus Danio rerio Canis lupus familiaris Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17q11.2





GO Molecular Function

enzyme binding | galactose binding | monosaccharide binding | disaccharide binding | carbohydrate binding | protein binding | oligosaccharide binding | small molecule binding

GO Biological Process

positive regulation of immune response | negative regulation of leukocyte activation | regulation of leukocyte chemotaxis | regulation of ERK1 and ERK2 cascade | regulation of interleukin-1 beta production | negative regulation of intracellular transport | positive regulation of locomotion | regulation of cysteine-type endopeptidase activity | response to virus | negative regulation of immune system process | response to cytokine | response to interleukin-1 | regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation | negative regulation of activated T cell proliferation | immune response-regulating signaling pathway | response to lipopolysaccharide | regulation of cellular localization | intracellular signal transduction | positive regulation of apoptotic process | regulation of localization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | toll-like receptor 2 signaling pathway | regulation of immune system process | myeloid cell differentiation | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | positive regulation of developmental process | positive regulation of lymphocyte activation | cell differentiation | regulation of T cell differentiation | defense response | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | regulation of leukocyte mediated cytotoxicity | positive regulation of interleukin-1 beta secretion | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | positive regulation of protein secretion | positive regulation of viral life cycle | positive regulation of T cell differentiation | positive regulation of dendritic cell apoptotic process | innate immune response-activating signal transduction | cellular process | toll-like receptor signaling pathway | positive regulation of dendritic cell differentiation | regulation of cell motility | positive regulation of immune effector process | female pregnancy | tolerance induction | immune system development | multicellular organismal reproductive process | negative regulation of innate immune response | regulation of chemotaxis | negative regulation of secretion | regulation of proteolysis | positive regulation of T cell apoptotic process | regulation of interleukin-10 secretion | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of T cell proliferation | regulation of cell differentiation | negative regulation of CD4-positive, alpha-beta T cell activation | negative regulation of mast cell activation | regulation of lymphocyte apoptotic process | positive regulation of interleukin-8 production | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | negative regulation of mononuclear cell proliferation | positive regulation of dendritic cell chemotaxis | positive regulation of interferon-gamma production | negative regulation of tumor necrosis factor production | positive regulation of cellular protein metabolic process | positive regulation of interleukin-4 production | regulation of mast cell degranulation | MAPK cascade | cellular response to interferon-gamma | positive regulation of tumor necrosis factor production | regulation of peptide secretion | response to stimulus | positive regulation of interleukin-1 beta production | positive regulation of NIK/NF-kappaB signaling | regulation of regulatory T cell differentiation | regulation of interleukin-8 secretion | positive regulation of innate immune response | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | signal transduction by protein phosphorylation | negative regulation of cell adhesion | regulation of CD4-positive, alpha-beta T cell activation | response to stress | negative regulation of tumor necrosis factor superfamily cytokine production | negative regulation of lymphocyte activation | positive regulation of lymphocyte proliferation | regulation of cell proliferation | positive regulation of activated T cell autonomous cell death | negative regulation of alpha-beta T cell proliferation | negative regulation of interferon-gamma production | positive regulation of cell-cell adhesion | positive regulation of cysteine-type endopeptidase activity | positive regulation of cell activation | activation of innate immune response | reproduction | positive regulation of cytokine secretion | positive regulation of proteolysis | response to molecule of bacterial origin | positive regulation of T cell activation | immune response-activating signal transduction | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | hemopoiesis | protein modification process | regulation of peptide transport | regulation of cell adhesion | macromolecule modification | regulation of intracellular transport | regulation of lymphocyte differentiation | stress-activated protein kinase signaling cascade | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | leukocyte differentiation | regulation of cellular response to stress | locomotion | positive regulation of mononuclear cell proliferation | response to external biotic stimulus | system development | regulation of interleukin-4 production | regulation of viral entry into host cell | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | pattern recognition receptor signaling pathway | negative regulation of secretion by cell | positive regulation of viral process | multicellular organism development | positive regulation of lymphocyte differentiation | positive regulation of tumor necrosis factor secretion | regulation of peptidase activity | regulation of MAPK cascade | phosphorus metabolic process | regulation of catalytic activity | regulation of phosphorylation | regulation of CD4-positive, alpha-beta T cell differentiation | regulation of T cell activation | negative regulation of natural killer cell mediated cytotoxicity | positive regulation of alpha-beta T cell differentiation | regulation of activated T cell proliferation | regulation of gene expression | positive regulation of chemotaxis | negative regulation of CD4-positive, alpha-beta T cell proliferation | positive regulation of secretion | negative regulation of chemokine production | cellular response to stress | response to lipid | myeloid leukocyte differentiation | negative regulation of cytokine production | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | positive regulation of alpha-beta T cell proliferation | regulation of lymphocyte activation | regulation of interleukin-12 secretion | regulation of mast cell activation | regulation of nitrogen compound metabolic process | negative regulation of T cell activation | regulation of cell migration | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of interleukin-12 production | positive regulation of intracellular signal transduction | regulation of cellular component movement | positive regulation of interleukin-13 production | positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation | positive regulation of hydrolase activity | positive regulation of cell differentiation | positive regulation of CD4-positive, alpha-beta T cell proliferation | positive regulation of cell migration | cellular response to cytokine stimulus | stress-activated MAPK cascade | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | positive regulation of monocyte chemotactic protein-1 production | negative regulation of immune response | phosphorylation | positive regulation of interleukin-1 secretion | positive regulation of endopeptidase activity | positive regulation of chemokine production | positive regulation of leukocyte apoptotic process | regulation of apoptotic signaling pathway | protein phosphorylation | regulation of tumor necrosis factor production | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of leukocyte migration | phosphate-containing compound metabolic process | response to bacterium | regulation of interleukin-1 production | negative regulation of cell-cell adhesion | positive regulation of interleukin-10 secretion | cell communication | regulation of cellular metabolic process | regulation of dendritic cell chemotaxis | positive regulation of interleukin-1 production | positive regulation of leukocyte chemotaxis | regulation of alpha-beta T cell differentiation | negative regulation of cell activation | regulation of T cell apoptotic process | inflammatory response | regulation of NIK/NF-kappaB signaling | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | positive regulation of transport | negative regulation of mast cell activation involved in immune response | cellular response to virus | regulation of viral process | p38MAPK cascade | positive regulation of molecular function | negative regulation of exocytosis | regulation of cytokine secretion | multicellular organism reproduction | maternal process involved in female pregnancy | positive regulation of transforming growth factor beta production | activation of immune response | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of innate immune response | mature conventional dendritic cell differentiation | regulation of hemopoiesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | regulation of exocytosis | anatomical structure development | metabolic process | dendritic cell differentiation | regulation of interleukin-1 beta secretion | negative regulation of leukocyte proliferation | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | regulation of interleukin-5 production | regulation of vesicle-mediated transport | regulation of secretion | positive regulation of cell death | toll-like receptor 4 signaling pathway | positive regulation of interleukin-6 production | immune response | positive regulation of interleukin-8 secretion | organic substance metabolic process | negative regulation of gene expression | animal organ development | regulation of cell activation | positive regulation of NF-kappaB transcription factor activity | regulation of protein secretion | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | positive regulation of programmed cell death | regulation of tumor necrosis factor secretion | regulation of phosphate metabolic process | response to interferon-gamma | positive regulation of cytokine production | regulation of regulated secretory pathway | positive regulation of MAPK cascade | regulation of natural killer cell mediated cytotoxicity | positive regulation of lymphocyte apoptotic process | positive regulation of protein transport | regulation of stress-activated MAPK cascade | regulation of cell communication | positive regulation of interleukin-10 production | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | positive regulation of viral entry into host cell | regulation of T cell proliferation | positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | positive regulation of CD4-positive, alpha-beta T cell differentiation | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | positive regulation of regulatory T cell differentiation | regulation of endopeptidase activity | response to biotic stimulus | regulation of developmental process | developmental process | positive regulation of alpha-beta T cell activation | cellular protein modification process | positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response | negative regulation of alpha-beta T cell activation | regulation of monocyte chemotactic protein-1 production | regulation of chemokine production | regulation of transport | negative regulation of cell proliferation | regulation of cell-cell adhesion | positive regulation of interleukin-13 secretion | innate immune response | regulation of dendritic cell differentiation | ERK1 and ERK2 cascade | positive regulation of metabolic process | regulation of interferon-gamma production | negative regulation of lymphocyte proliferation | immune system process | regulation of natural killer cell mediated immunity | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cell motility | positive regulation of CD4-positive, alpha-beta T cell activation | regulation of viral life cycle | regulation of interleukin-6 production | positive regulation of interferon-gamma secretion | chemotaxis | natural killer cell tolerance induction | positive regulation of leukocyte cell-cell adhesion | positive regulation of interleukin-12 secretion | regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of apoptotic signaling pathway | response to other organism | negative regulation of mast cell degranulation | positive regulation of signaling | signal transduction | regulation of signaling | regulation of p38MAPK cascade | positive regulation of gene expression | macromolecule metabolic process | positive regulation of interleukin-6 secretion | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cytosol | intracellular