QuickView for Gas2 (gene)

Gene Symbol:

GAS2 Homo sapiens

Full name:

growth arrest specific 2

Synonyms:

GAS-2, growth arrest-specific protein 2

Genomic Location:

Chr 11: 22646230-22791123

Description:

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants.

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CTTGTAT_MIR381 ,  HNF1_01 ,  AP3_Q6 ,  TGCCTTA_MIR124A ,  GFI1_01 ,  POU3F2_02 ,  TAATTA_CHX10_01 ,  RORA2_01 ,  TGATTTRY_GFI1_01 ,  PAX2_02 ,  HNF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u

Cytogenetic Map:

11p14.3

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