QuickView for Grb7 (gene)

Gene Symbol:

GRB7 Homo sapiens

Full name:

growth factor receptor bound protein 7

Synonyms:

growth factor receptor-bound protein 7, B47, GRB7 adapter protein, epidermal growth factor receptor GRB-7

Genomic Location:

Chr 17: 35147713-35157064

Description:

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin si...

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The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

FOXO1_02 ,  E12_Q6 ,  POU6F1_01 ,  RTAAACA_FREAC2_01 ,  TTANTCA_UNKNOWN ,  RYTTCCTG_ETS2_B ,  HFH3_01 ,  GCANCTGNY_MYOD_Q6 ,  AAAYWAACM_HFH4_01 ,  FOXD3_01 ,  HFH1_01 ,  TEL2_Q6 ,  GATAAGR_GATA_C ,  CDPCR3HD_01 ,  FOXO3_01 ,  FREAC3_01 ,  CAGGTG_E12_Q6 ,  HNF4_Q6 ,  CDPCR1_01 ,  GGGCGGR_SP1_Q6 ,  FOXO1_01 ,  GCM_Q2 ,  MEIS1_01 ,  TGTTTGY_HNF3_Q6 ,  TTGTTT_FOXO4_01 ,  STAT5A_04 ,  CP2_02 ,  RGTTAMWNATT_HNF1_01 ,  GGCCAGT_MIR193A_MIR193B ,  FOXO4_02 ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-193

Cytogenetic Map:

17q12

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