QuickView for HD11 (gene)
- Gene Symbol:
- HDAC11
Homo sapiens - Full name:
- histone deacetylase 11
- Synonyms:
- HD11, histone deacetylase 11
- Genomic Location:
- Chr 3: 13496824-13521834
- Description:
-
This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Gallus gallus , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
3p25.1
GO Molecular Function
histone deacetylase activity (H3-K14 specific) | NAD-dependent histone deacetylase activity (H3-K14 specific) | hydrolase activity | protein deacetylase activity | catalytic activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | NAD-dependent protein deacetylase activity | histone deacetylase activity | NAD-dependent histone deacetylase activity | protein binding | transcription factor binding | deacetylase activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO Biological Process
RNA metabolic process | histone modification | cell differentiation | nervous system development | histone deacetylation | neurogenesis | cellular process | chromatin organization | histone deacetylase activity (H3-K14 specific) | regulation of cellular process | regulation of metabolic process | gliogenesis | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | oligodendrocyte development | NAD-dependent histone deacetylase activity (H3-K14 specific) | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | protein modification process | protein deacetylase activity | cellular biosynthetic process | macromolecule modification | histone H3 deacetylation | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | multicellular organism development | NAD-dependent protein deacetylase activity | regulation of gene expression | histone deacetylase activity | regulation of nitrogen compound metabolic process | biosynthetic process | protein deacetylation | aromatic compound biosynthetic process | glial cell differentiation | NAD-dependent histone deacetylase activity | regulation of cellular metabolic process | regulation of RNA metabolic process | protein metabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | oligodendrocyte differentiation | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | covalent chromatin modification | regulation of transcription, DNA-templated | glial cell development | cell development | cellular protein metabolic process | cellular macromolecule biosynthetic process | developmental process | organelle organization | cellular protein modification process | heterocycle metabolic process | central nervous system development | chromosome organization | cellular metabolic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | intracellular organelle | protein-containing complex | histone deacetylase complex | nucleoplasm | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | intracellular | membrane
