QuickView for HIP1R (gene)
- Gene Symbol:
- HIP1R
Homo sapiens - Full name:
- huntingtin interacting protein 1 related
- Synonyms:
- HIP12, HIP3, ILWEQ, huntingtin-interacting protein 1-related protein, HIP-12, HIP1-related protein, huntingtin interacting protein 12
- Genomic Location:
- Chr 12: 121885992-121913460
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
12q24.31
GO Molecular Function
actin binding | actin filament binding | phosphatidylinositol-4,5-bisphosphate binding | clathrin binding | protein-containing complex binding | lipid binding | SH3 domain binding | phospholipid binding | phosphatidylinositol-3,4-bisphosphate binding | protein domain specific binding | cytoskeletal protein binding | protein binding, bridging | anion binding | clathrin light chain binding | phosphatidylinositol bisphosphate binding | endocytic adaptor activity | identical protein binding | protein heterodimerization activity | ion binding | phosphatidylinositol-3,4,5-trisphosphate binding | molecular adaptor activity | protein binding | protein homodimerization activity | protein dimerization activity | phosphatidylinositol binding | phosphatidylinositol-3,5-bisphosphate binding | clathrin adaptor activity | cargo receptor activity | phosphatidylinositol phosphate binding
GO Biological Process
regulation of supramolecular fiber organization | regulation of cysteine-type endopeptidase activity | actin filament-based process | positive regulation of cellular component organization | regulation of clathrin-dependent endocytosis | positive regulation of apoptotic process | protein stabilization | regulation of localization | regulation of programmed cell death | actin cytoskeleton organization | establishment of localization | negative regulation of cellular process | negative regulation of actin nucleation | regulation of organelle organization | regulation of actin polymerization or depolymerization | membrane organization | cellular process | localization | regulation of digestive system process | negative regulation of apoptotic process | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of binding | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | cellular component organization | positive regulation of protein binding | regulation of actin filament length | positive regulation of protein metabolic process | positive regulation of peptidase activity | positive regulation of cysteine-type endopeptidase activity | programmed cell death | supramolecular fiber organization | positive regulation of proteolysis | regulation of cellular component size | cellular component assembly | mitochondrion organization | positive regulation of ERBB signaling pathway | positive regulation of mitochondrion organization | apoptotic process | system development | regulation of signal transduction | positive regulation of organelle organization | regulation of protein stability | regulation of actin cytoskeleton organization | multicellular organism development | regulation of peptidase activity | regulation of actin filament organization | actin filament organization | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | regulation of catalytic activity | regulation of receptor-mediated endocytosis | positive regulation of receptor-mediated endocytosis | regulation of mitochondrial membrane permeability | endocytic adaptor activity | positive regulation of cellular metabolic process | negative regulation of actin filament polymerization | mitochondrial transport | regulation of platelet-derived growth factor receptor signaling pathway | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of gastric acid secretion | positive regulation of protein complex assembly | vesicle-mediated transport | positive regulation of hydrolase activity | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | cellular protein-containing complex assembly | regulation of apoptotic signaling pathway | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of mitochondrion organization | mitochondrial membrane organization | regulation of cellular metabolic process | regulation of actin filament polymerization | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of transport | positive regulation of molecular function | protein-containing complex assembly | negative regulation of protein polymerization | digestive system development | import into cell | anatomical structure development | clathrin coat assembly | positive regulation of platelet-derived growth factor receptor signaling pathway | activation of cysteine-type endopeptidase activity involved in apoptotic process | negative regulation of programmed cell death | negative regulation of cytoskeleton organization | regulation of vesicle-mediated transport | endocytosis | regulation of secretion | positive regulation of cell death | regulation of actin nucleation | negative regulation of protein complex assembly | positive regulation of cellular component biogenesis | regulation of epidermal growth factor receptor signaling pathway | cell death | regulation of Arp2/3 complex-mediated actin nucleation | positive regulation of programmed cell death | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | cytoskeleton organization | positive regulation of binding | regulation of cell communication | regulation of membrane permeability | regulation of protein binding | regulation of ERBB signaling pathway | regulation of endocytosis | clathrin adaptor activity | positive regulation of epidermal growth factor receptor signaling pathway | regulation of endopeptidase activity | receptor-mediated endocytosis | developmental process | organelle organization | negative regulation of Arp2/3 complex-mediated actin nucleation | regulation of transport | negative regulation of supramolecular fiber organization | positive regulation of metabolic process | regulation of actin filament-based process | cargo receptor activity | positive regulation of platelet-derived growth factor receptor-beta signaling pathway | regulation of cell death | negative regulation of cell death | positive regulation of clathrin coat assembly | positive regulation of endocytosis | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | regulation of cytoskeleton organization | positive regulation of signaling | regulation of signaling | multicellular organismal process
GO Cellular Component
dendritic spine | clathrin coat of endocytic vesicle | dendrite | intracellular membrane-bounded organelle | synapse | apical plasma membrane | neuron projection | clathrin-coated endocytic vesicle membrane | ruffle | actin cortical patch | endocytic vesicle membrane | clathrin-coated vesicle membrane | somatodendritic compartment | organelle membrane | cell projection membrane | vesicle coat | clathrin-coated vesicle | clathrin coat of coated pit | cytoplasmic vesicle | cell body | cell | neuronal cell body | plasma membrane protein complex | synaptic membrane | ruffle membrane | AP-2 adaptor complex | cytoplasm | clathrin-coated endocytic vesicle | cortical cytoskeleton | dendrite cytoplasm | intracellular organelle | actin cytoskeleton | dendritic tree | leading edge membrane | apical part of cell | AP-type membrane coat adaptor complex | protein-containing complex | cell projection | clathrin adaptor complex | endomembrane system | neuron spine | postsynapse | plasma membrane bounded cell projection cytoplasm | plasma membrane | cell leading edge | vesicle | perinuclear region of cytoplasm | postsynaptic density | clathrin-coated pit | asymmetric synapse | endocytic patch | cytoplasmic region | mitochondrion | cortical actin cytoskeleton | coated vesicle membrane | cell cortex | membrane-bounded organelle | clathrin coat | organelle | postsynaptic specialization | vesicle membrane | cell periphery | clathrin vesicle coat | cytosol | intracellular vesicle | cytoskeleton | endocytic vesicle | intracellular | membrane | cytoplasmic vesicle membrane | membrane coat | coated vesicle
