QuickView for HMGN2;jsessionid=6A6C250B9D09313D3DBBA9DB8CCCA049 (gene)

Gene Symbol:

HMGN2 Homo sapiens

Full name:

high mobility group nucleosomal binding domain 2

Synonyms:

HMG17, non-histone chromosomal protein HMG-17, high mobility group nucleosome-binding domain-containing protein 2, high mobility group protein N2, high-mobility group (nonhistone chromosomal) protein 17, nonhistone chromosomal protein HMG-17

Genomic Location:

Chr 1: 26671489-26675720

Description:

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi.

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  PR_Q2 ,  POU6F1_01 ,  GATTGGY_NFY_Q6_01 ,  MYOD_Q6_01 ,  SP1_01 ,  MCAATNNNNNGCG_UNKNOWN ,  MYOD_01 ,  USF_Q6 ,  TTANTCA_UNKNOWN ,  ARNT_01 ,  MAZ_Q6 ,  MYC_Q2 ,  E2F1_Q4_01 ,  CACGTG_MYC_Q2 ,  GCANCTGNY_MYOD_Q6 ,  AAAYWAACM_HFH4_01 ,  NGFIC_01 ,  YATTNATC_UNKNOWN ,  E2F_Q6_01 ,  SRY_01 ,  AMEF2_Q6 ,  MAF_Q6 ,  EGR2_01 ,  E2F1_Q4 ,  HEB_Q6 ,  GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  CEBP_Q2 ,  CACCCBINDINGFACTOR_Q6 ,  E2F_Q6 ,  CAGGTA_AREB6_01 ,  TEF1_Q6 ,  NFY_Q6_01 ,  E2F1_Q6_01 ,  RFX1_02 ,  CAGGTG_E12_Q6 ,  E47_02 ,  AP4_Q6 ,  AP4_01 ,  TATA_C ,  E2F_Q4 ,  CAGGGTC_MIR504 ,  NF1_Q6 ,  GGGCGGR_SP1_Q6 ,  GGCNKCCATNK_UNKNOWN ,  USF_C ,  HIF1_Q5 ,  NERF_Q2 ,  E2F1_Q3_01 ,  NKX25_02 ,  TGCCAAR_NF1_Q6 ,  SPZ1_01 ,  NF1_Q6_01 ,  TGTTTGY_HNF3_Q6 ,  USF_01 ,  E2F_03 ,  YCATTAA_UNKNOWN ,  E2F_Q4_01 ,  RNGTGGGC_UNKNOWN ,  AATGTGA_MIR23A_MIR23B ,  NMYC_01 ,  AP2_Q6 ,  CEBP_Q3 ,  USF_Q6_01 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  AP4_Q6_01 ,  E2F1DP1RB_01 ,  CHOP_01 ,  MYOGENIN_Q6 ,  MSX1_01 ,  WWTAAGGC_UNKNOWN ,  CTGCAGY_UNKNOWN ,  E2F1_Q3 ,  E2F_Q2 ,  TGACAGNY_MEIS1_01 ,  EGR1_01 ,  CAGCTG_AP4_Q5 ,  MMEF2_Q6 ,  USF2_Q6 ,  AACTTT_UNKNOWN ,  AP4_Q5 ,  E2F_Q3 ,  CRX_Q4 ,  PPARA_02 ,  E2F_Q3_01 ,  HIF1_Q3 ,  EGR3_01 ,  PAX4_01 ,  ETF_Q6 ,  GTCAACC_MIR3805P ,  LMO2COM_01 ,  LBP1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-380-5p ,  Predicted Gene Targets for miR-504 ,  Predicted Gene Targets for miR-544

Cytogenetic Map:

1p36.11

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