QuickView for HNRNPAB;jsessionid=74A5D62AB4B19463C639475813FA283F (gene)

Gene Symbol:

HNRNPAB Homo sapiens

Full name:

heterogeneous nuclear ribonucleoprotein A/B

Synonyms:

ABBP1, HNRPAB, heterogeneous nuclear ribonucleoprotein A/B, ABBP-1, APOBEC1-binding protein 1, apobec-1 binding protein 1, apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1-binding protein 1, hnRNP A/B, hnRNP type A/B protein

Genomic Location:

Chr 5: 177564114-177570790

Description:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA me...

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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATF4_Q2 ,  CREB_Q3 ,  TATAAA_TATA_01 ,  CREB_02 ,  GGGCGGR_SP1_Q6 ,  CAGCAGG_MIR370 ,  YGCGYRCGC_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  HNF4_01_B ,  TCCAGAG_MIR518C

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-370 ,  Predicted Gene Targets for miR-203

Cytogenetic Map:

5q35.3

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