QuickView for HNRNPR;jsessionid=688A9DE411769326040519C96A86C3CD (gene)
- Gene Symbol:
- HNRNPR
Homo sapiens - Full name:
- heterogeneous nuclear ribonucleoprotein R
- Synonyms:
- HNRPR, hnRNP-R, heterogeneous nuclear ribonucleoprotein R
- Genomic Location:
- Chr 1: 23508863-23543440
- Description:
-
This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1p36.12
GO Molecular Function
nucleic acid binding | mRNA binding | organic cyclic compound binding | protein binding | mRNA 3'-UTR binding | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | RNA processing | negative regulation of cellular process | cellular process | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | positive regulation of mRNA catabolic process | regulation of mRNA stability | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | RNA splicing | RNA splicing, via transesterification reactions | posttranscriptional regulation of gene expression | circadian rhythm | rhythmic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | mRNA metabolic process | nitrogen compound metabolic process | negative regulation of catalytic activity | regulation of catalytic activity | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of RNA stability | regulation of cellular protein metabolic process | mRNA destabilization | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | regulation of mRNA catabolic process | negative regulation of cellular protein metabolic process | gene expression | RNA destabilization | negative regulation of translation | negative regulation of protein metabolic process | negative regulation of molecular function | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | mRNA processing | regulation of translation | mRNA splicing, via spliceosome | macromolecule metabolic process
GO Cellular Component
dendrite | intracellular membrane-bounded organelle | synapse | catalytic complex | catalytic step 2 spliceosome | neuron projection | somatodendritic compartment | cell | nuclear lumen | distal axon | nucleolus | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | presynapse | protein-containing complex | cell projection | endomembrane system | nucleoplasm | ribonucleoprotein complex | spliceosomal complex | site of polarized growth | membrane-bounded organelle | nucleus | organelle | axon terminus | axon | membrane-enclosed lumen | growth cone | neuron projection terminus | intracellular
