QuickView for HOXA11;jsessionid=F634A41D3DD3DFC5A010FA48F9C98A1E (gene)

Gene Symbol:

HOXA11 Homo sapiens

Full name:

homeobox A11

Synonyms:

HOX1, HOX1I, RUSAT1, homeobox protein Hox-A11, homeo box 1I, homeobox protein HOXA11, homeobox protein Hox-1I

Genomic Location:

Chr 7: 27187301-27191360

Description:

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcripti...

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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

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Orthologs:

Mus musculus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Rattus norvegicus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  FOXO1_02 ,  POU6F1_01 ,  RTAAACA_FREAC2_01 ,  FREAC7_01 ,  HNF3ALPHA_Q6 ,  AP1_C ,  TGANTCA_AP1_C ,  TAL1ALPHAE47_01 ,  RYTTCCTG_ETS2_B ,  ARNT_01 ,  FOX_Q2 ,  P53_DECAMER_Q2 ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  HFH3_01 ,  EFC_Q6 ,  HEN1_01 ,  FOXO4_01 ,  POU3F2_01 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  AAAYWAACM_HFH4_01 ,  FOXD3_01 ,  HFH1_01 ,  MAX_01 ,  HP1SITEFACTOR_Q6 ,  XBP1_01 ,  CAGTGTT_MIR141_MIR200A ,  AREB6_04 ,  WGTTNNNNNAAA_UNKNOWN ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  MEIS1BHOXA9_01 ,  NFKAPPAB_01 ,  AP1_Q6 ,  ZIC3_01 ,  SREBP1_Q6 ,  CTTTGA_LEF1_Q2 ,  PBX1_01 ,  E2F1_Q4 ,  TCF4_Q5 ,  TATAAA_TATA_01 ,  MYCMAX_02 ,  CEBPDELTA_Q6 ,  NFE2_01 ,  AP1_Q6_01 ,  TAL1BETAE47_01 ,  CDP_02 ,  PAX4_02 ,  SREBP1_01 ,  GGATTA_PITX2_Q2 ,  CEBP_01 ,  FREAC3_01 ,  P53_02 ,  CDX2_Q5 ,  CAGGTG_E12_Q6 ,  AP4_01 ,  GR_Q6 ,  AP1FJ_Q2 ,  NKX62_Q2 ,  HNF3_Q6 ,  HNF4_Q6 ,  RRAGTTGT_UNKNOWN ,  MYCMAX_01 ,  HNF3B_01 ,  ACCAAAG_MIR9 ,  CATRRAGC_UNKNOWN ,  FOXJ2_01 ,  CCCNNGGGAR_OLF1_01 ,  NKX61_01 ,  MGGAAGTG_GABP_B ,  FOXO1_01 ,  HFH4_01 ,  TGTTTGY_HNF3_Q6 ,  HFH8_01 ,  USF_01 ,  AP1_Q4 ,  OCT1_06 ,  PTF1BETA_Q6 ,  AREB6_03 ,  RNGTGGGC_UNKNOWN ,  AATGTGA_MIR23A_MIR23B ,  EN1_01 ,  FREAC2_01 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  ATATGCA_MIR448 ,  CHOP_01 ,  CART1_01 ,  MSX1_01 ,  RTTTNNNYTGGM_UNKNOWN ,  GATA1_05 ,  MEF2_03 ,  TEF_Q6 ,  TATA_01 ,  TTCYNRGAA_STAT5B_01 ,  TAL1BETAITF2_01 ,  AP1_Q2 ,  CTTTGT_LEF1_Q2 ,  MMEF2_Q6 ,  CDC5_01 ,  AACTTT_UNKNOWN ,  USF_02 ,  TCF1P_Q6 ,  AP1_Q4_01 ,  NFKB_Q6 ,  NFKB_C ,  FREAC4_01 ,  HNF6_Q6 ,  TATTATA_MIR374 ,  LMO2COM_01 ,  STAT5A_02 ,  MYB_Q3

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-339 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-410

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miRNA binding sites
(Source: miRecords):

hsa-miR-181a Targeted Genes

Cytogenetic Map:

7p15.2

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