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QuickView for HOXB13;jsessionid=DBD84024EF7081E567A61853680FB962 (gene)


Gene Symbol:
HOXB13 Homo sapiens Homo sapiens
Full name:
homeobox B13
Synonyms:
PSGD, homeobox protein Hox-B13
Genomic Location:
Chr 17: 44157124-44161110
Description:
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal an...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17q21.32


Transcripts Names
NM_006361
Protein Names
Q99810
Q92826
B2R878
Q4KR72
Q96QM4



GO Molecular Function

sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | nucleic acid binding | nucleotide binding | DNA binding | organic cyclic compound binding | DNA-binding transcription factor activity | methyl-CpG binding | heterocyclic compound binding | small molecule binding

GO Biological Process

RNA metabolic process | developmental process involved in reproduction | morphogenesis of an epithelium | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | blood vessel morphogenesis | cellular process | cell maturation | reproductive system development | negative regulation of nucleic acid-templated transcription | negative regulation of cellular metabolic process | tissue development | regulation of cellular process | epithelial cell maturation involved in prostate gland development | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | prostate gland epithelium morphogenesis | urogenital system development | response to stimulus | vasculature development | gland morphogenesis | response to stress | cellular nitrogen compound biosynthetic process | tube morphogenesis | epithelial cell development | reproduction | cardiovascular system development | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | blood vessel development | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | epithelial cell differentiation involved in prostate gland development | regulation of gene expression | response to ketone | response to lipid | branching involved in prostate gland morphogenesis | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | angiogenesis | epidermis development | epithelial cell maturation | regulation of cellular metabolic process | response to testosterone | regulation of RNA metabolic process | DNA-binding transcription factor activity | regulation of growth | response to organic substance | gland development | tissue morphogenesis | response to wounding | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | developmental maturation | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | prostate gland morphogenesis | transcription, DNA-templated | morphogenesis of a branching epithelium | anatomical structure formation involved in morphogenesis | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | morphogenesis of a branching structure | anatomical structure morphogenesis | prostate gland development | cellular macromolecule biosynthetic process | reproductive structure development | developmental process | negative regulation of transcription by RNA polymerase II | tube development | epithelial cell differentiation | heterocycle metabolic process | cellular metabolic process | circulatory system development | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular