QuickView for HRH4 (gene)
- Gene Symbol:
- HRH4
Homo sapiens - Full name:
- histamine receptor H4
- Synonyms:
- AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R, histamine H4 receptor, G-protein coupled receptor 105, SP9144, pfi-013
- Genomic Location:
- Chr 18: 20294591-20313919
- Description:
-
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The pr...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Gallus gallus , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
18q11.2
GO Molecular Function
neurotransmitter receptor activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | G-protein coupled amine receptor activity | acetylcholine receptor activity | signaling receptor activity | G-protein coupled acetylcholine receptor activity | G-protein coupled serotonin receptor activity | histamine receptor activity
GO Biological Process
response to hormone | defense response | response to drug | cellular chemical homeostasis | cellular process | cellular homeostasis | acetylcholine receptor signaling pathway | chemical synaptic transmission | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | calcium ion homeostasis | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | G-protein coupled receptor activity | response to stimulus | response to stress | G-protein coupled amine receptor activity | G-protein coupled receptor signaling pathway | cell-cell signaling | metal ion homeostasis | response to nitrogen compound | cellular response to hormone stimulus | regulation of signal transduction | regulation of MAPK cascade | G-protein coupled acetylcholine receptor signaling pathway | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of phosphorylation | cellular response to ammonium ion | synaptic signaling | cellular ion homeostasis | response to ammonium ion | response to acetylcholine | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | cation homeostasis | cellular response to drug | G-protein coupled acetylcholine receptor activity | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | inflammatory response | regulation of protein metabolic process | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway | response to organic substance | regulation of intracellular signal transduction | chemical homeostasis | ion homeostasis | regulation of phosphate metabolic process | G-protein coupled serotonin receptor activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | histamine receptor activity | G-protein coupled serotonin receptor signaling pathway | serotonin receptor signaling pathway | cellular metal ion homeostasis | cellular response to organic substance | divalent inorganic cation homeostasis | signal transduction | regulation of signaling | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cell | intrinsic component of membrane | dendritic tree | cell projection | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane
