QuickView for HSD17B11;jsessionid=B66D519AF1636C27062BF0637A38E225 (gene)
- Gene Symbol:
- HSD17B11
Homo sapiens - Full name:
- hydroxysteroid 17-beta dehydrogenase 11
- Synonyms:
- 17-BETA-HSD11, 17-BETA-HSDXI, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2, estradiol 17-beta-dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase type XI, CTCL tumor antigen HD-CL-03, CTCL-associated antigen HD-CL-03, cutaneous T-cell lymphoma-associated antigen HD-CL-03, dehydrogenase/reductase SDR family member 8, retinal short-chain dehydrogenase/reductase 2, short chain dehydrogenase/reductase family 16C member 2
- Genomic Location:
- Chr 4: 88476715-88531479
- Description:
-
Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
4q22.1
GO Molecular Function
oxidoreductase activity, acting on CH-OH group of donors | steroid dehydrogenase activity | estradiol 17-beta-dehydrogenase activity | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | catalytic activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity
GO Biological Process
oxidoreductase activity, acting on CH-OH group of donors | steroid dehydrogenase activity | estradiol 17-beta-dehydrogenase activity | estrogen biosynthetic process | estrogen metabolic process | cellular process | organic substance catabolic process | catabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | androgen metabolic process | cellular biosynthetic process | hormone biosynthetic process | steroid catabolic process | lipid metabolic process | regulation of hormone levels | biosynthetic process | lipid biosynthetic process | androgen catabolic process | hormone catabolic process | metabolic process | oxidation-reduction process | lipid catabolic process | organic substance metabolic process | steroid metabolic process | hormone metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | cellular metabolic process | oxidoreductase activity
GO Cellular Component
cell | cytoplasm | intracellular organelle | lipid droplet | extracellular region | organelle | cytosol | intracellular
