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QuickView for HSPA13 (gene)


Gene Symbol:
HSPA13 Homo sapiens Homo sapiens
Full name:
heat shock protein family A (Hsp70) member 13
Synonyms:
STCH, heat shock 70 kDa protein 13, heat shock protein 70kDa family, member 13, microsomal stress 70 protein ATPase core, stress 70 protein chaperone, microsome-associated, 60kD, stress 70 protein chaperone, microsome-associated, 60kDa, stress-70 protein chaperone microsome-associated 60 kDa protein, testis secretory sperm-binding protein Li 199a
Genomic Location:
Chr 21: 14665307-14677380
Description:
The protein encoded by this gene is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. The encoded protein contains an ATPase domain and has been ...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 21
21q11.2


Transcripts Names
NM_006948
Protein Names
Q8NE40
A0A140VK72
P48723
B2R616



GO Molecular Function

ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | unfolded protein binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ion binding | organic cyclic compound binding | protein binding involved in protein folding | purine ribonucleoside triphosphate binding | protein binding | misfolded protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heat shock protein binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

response to endoplasmic reticulum stress | 'de novo' posttranslational protein folding | proteolysis | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | chaperone-mediated protein folding | endoplasmic reticulum unfolded protein response | regulation of cellular process | catabolic process | cellular response to unfolded protein | response to topologically incorrect protein | cellular response to topologically incorrect protein | response to stimulus | response to stress | cellular protein catabolic process | response to temperature stimulus | proteasomal protein catabolic process | response to nitrogen compound | nitrogen compound metabolic process | cellular response to stress | protein catabolic process | cellular response to heat | 'de novo' protein folding | cell communication | protein binding involved in protein folding | proteasome-mediated ubiquitin-dependent protein catabolic process | ERAD pathway | protein metabolic process | response to organic substance | cellular macromolecule catabolic process | metabolic process | organic substance metabolic process | protein folding | response to heat | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | signaling | cellular protein metabolic process | response to unfolded protein | chaperone cofactor-dependent protein refolding | response to organonitrogen compound | protein refolding | ubiquitin-dependent ERAD pathway | cellular metabolic process | cellular response to organic substance | modification-dependent protein catabolic process | signal transduction | macromolecule metabolic process

GO Cellular Component

endoplasmic reticulum chaperone complex | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | protein-containing complex | endomembrane system | vesicle | endoplasmic reticulum lumen | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | intracellular | membrane