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QuickView for HTR1A (gene)


Gene Symbol:
HTR1A Homo sapiens Homo sapiens
Full name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD, 5-hydroxytryptamine receptor 1A, 5-HT1a receptor, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled, guanine nucleotide-binding regulatory protein-coupled receptor
Genomic Location:
Chr 5: 63292034-63293302
Description:
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. M...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5
5q12.3


Transcripts Names
NM_000524
Protein Names
Q5ZGX3
Q6LAE7
P08908
A8K5W4



GO Molecular Function

neurotransmitter receptor activity | receptor-receptor interaction | cation binding | neurotransmitter binding | transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor binding | G-protein coupled amine receptor activity | serotonin binding | signaling receptor activity | ion binding | organic cyclic compound binding | amine binding | protein binding | G-protein coupled serotonin receptor activity | heterocyclic compound binding

GO Biological Process

regulation of blood vessel diameter | behavioral fear response | regulation of localization | defense response | phenol-containing compound metabolic process | cellular process | exploration behavior | chemical synaptic transmission | regulation of behavior | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | G-protein coupled receptor activity | response to stimulus | serotonin metabolic process | regulation of blood vessel size | response to stress | regulation of cell proliferation | G-protein coupled amine receptor activity | cellular nitrogen compound metabolic process | regulation of dopamine metabolic process | blood circulation | G-protein coupled receptor signaling pathway | cell-cell signaling | negative regulation of blood vessel diameter | regulation of catecholamine metabolic process | regulation of neurotransmitter levels | organic hydroxy compound metabolic process | nitrogen compound metabolic process | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of hormone levels | regulation of hormone secretion | synaptic signaling | regulation of nitrogen compound metabolic process | neurotransmitter metabolic process | cell proliferation | vasoconstriction | regulation of serotonin secretion | cell communication | regulation of cellular metabolic process | positive regulation of cell proliferation | regulation of tube size | multicellular organismal response to stress | fear response | metabolic process | regulation of tube diameter | regulation of secretion | behavior | organic substance metabolic process | G-protein coupled serotonin receptor activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | G-protein coupled serotonin receptor signaling pathway | regulation of ion transport | behavioral defense response | regulation of transport | serotonin receptor signaling pathway | heterocycle metabolic process | adenylate cyclase-inhibiting serotonin receptor signaling pathway | cellular metabolic process | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cell | intrinsic component of membrane | dendritic tree | cell projection | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane