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QuickView for HTR1A (gene)

Gene Symbol:
HTR1A Homo sapiens Homo sapiens
Full name:
5-hydroxytryptamine receptor 1A
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD, 5-hydroxytryptamine receptor 1A, 5-HT1a receptor, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled, guanine nucleotide-binding regulatory protein-coupled receptor
Genomic Location:
Chr 5: 63292034-63293302
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. M...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5

Transcripts Names
Protein Names

GO Molecular Function

neurotransmitter receptor activity | receptor-receptor interaction | cation binding | neurotransmitter binding | transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor binding | G-protein coupled amine receptor activity | serotonin binding | signaling receptor activity | ion binding | organic cyclic compound binding | amine binding | protein binding | G-protein coupled serotonin receptor activity | heterocyclic compound binding

GO Biological Process

regulation of blood vessel diameter | behavioral fear response | regulation of localization | defense response | phenol-containing compound metabolic process | cellular process | exploration behavior | chemical synaptic transmission | regulation of behavior | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | G-protein coupled receptor activity | response to stimulus | serotonin metabolic process | regulation of blood vessel size | response to stress | regulation of cell proliferation | G-protein coupled amine receptor activity | cellular nitrogen compound metabolic process | regulation of dopamine metabolic process | blood circulation | G-protein coupled receptor signaling pathway | cell-cell signaling | negative regulation of blood vessel diameter | regulation of catecholamine metabolic process | regulation of neurotransmitter levels | organic hydroxy compound metabolic process | nitrogen compound metabolic process | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of hormone levels | regulation of hormone secretion | synaptic signaling | regulation of nitrogen compound metabolic process | neurotransmitter metabolic process | cell proliferation | vasoconstriction | regulation of serotonin secretion | cell communication | regulation of cellular metabolic process | positive regulation of cell proliferation | regulation of tube size | multicellular organismal response to stress | fear response | metabolic process | regulation of tube diameter | regulation of secretion | behavior | organic substance metabolic process | G-protein coupled serotonin receptor activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | G-protein coupled serotonin receptor signaling pathway | regulation of ion transport | behavioral defense response | regulation of transport | serotonin receptor signaling pathway | heterocycle metabolic process | adenylate cyclase-inhibiting serotonin receptor signaling pathway | cellular metabolic process | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cell | intrinsic component of membrane | dendritic tree | cell projection | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane