QuickView for HoxC10 (gene)

Gene Symbol:

HOXC10 Homo sapiens

Full name:

homeobox C10

Synonyms:

HOX3I, homeobox protein Hox-C10, homeo box C10, homeobox protein Hox-3I, homeoprotein C10

Genomic Location:

Chr 12: 52665213-52670330

Description:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11...

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This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CGTSACG_PAX3_B ,  RTAAACA_FREAC2_01 ,  TGANTCA_AP1_C ,  CREBP1CJUN_01 ,  CREB_Q4_01 ,  GNCF_01 ,  OCT1_04 ,  AP3_Q6 ,  E2F1_Q4_01 ,  FOXO4_01 ,  E2F4DP1_01 ,  ATF4_Q2 ,  YATTNATC_UNKNOWN ,  AREB6_04 ,  AP2GAMMA_01 ,  STAT6_01 ,  AP2ALPHA_01 ,  AATGGAG_MIR136 ,  GATA1_04 ,  CREB_Q4 ,  TGACCTY_ERR1_Q2 ,  CREB_Q3 ,  WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  ATF_B ,  CREBP1_Q2 ,  TFIII_Q6 ,  CEBPB_01 ,  SOX9_B1 ,  LEF1_Q6 ,  E2F_Q6 ,  CAGGTA_AREB6_01 ,  GTGACGY_E4F1_Q6 ,  LFA1_Q6 ,  E2F1_Q6_01 ,  ATF_01 ,  CDX2_Q5 ,  YY1_01 ,  E2F_Q4 ,  GCAAAAA_MIR129 ,  ATF3_Q6 ,  STAT5A_03 ,  E2F1DP2_01 ,  CCCNNGGGAR_OLF1_01 ,  AAGWWRNYGGC_UNKNOWN ,  E4F1_Q6 ,  NKX61_01 ,  SPZ1_01 ,  AP2_Q3 ,  E2F1DP1_01 ,  E2F_Q4_01 ,  RNGTGGGC_UNKNOWN ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  ATF1_Q6 ,  E2F1DP1RB_01 ,  AFP1_Q6 ,  GATA1_05 ,  IRF7_01 ,  E2F_02 ,  CREB_Q2 ,  E2F1_Q3 ,  E2F4DP2_01 ,  CTTTGT_LEF1_Q2 ,  TAANNYSGCG_UNKNOWN ,  MMEF2_Q6 ,  AACTTT_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  TGACATY_UNKNOWN ,  PAX2_02 ,  E2F_Q3_01 ,  ELF1_Q6 ,  TGACCTTG_SF1_Q6 ,  CREB_Q2_01 ,  CREB_01 ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01 ,  SF1_Q6 ,  ATGTAGC_MIR221_MIR222

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-136 ,  Predicted Gene Targets for miR-221 ,  Predicted Gene Targets for miR-33 ,  Predicted Gene Targets for miR-450

Cytogenetic Map:

12q13.13

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