QuickView for Hoxd3 (gene)

Gene Symbol:

HOXD3 Homo sapiens

Full name:

homeobox D3

Synonyms:

HOX1D, HOX4, HOX4A, Hox-4.1, homeobox protein Hox-D3, Hox-4.1, mouse, homolog of, homeo box D3, homeobox protein Hox-4A

Genomic Location:

Chr 2: 176737051-176746072

Description:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arr...

View Full Description

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  HNF4ALPHA_Q6 ,  TTANTCA_UNKNOWN ,  TCANNTGAY_SREBP1_01 ,  AREB6_02 ,  MYOGNF1_01 ,  PPARA_01 ,  CATTGTYY_SOX9_B1 ,  NKX3A_01 ,  GCAAGGA_MIR502 ,  GCANCTGNY_MYOD_Q6 ,  TTTGTAG_MIR520D ,  YATTNATC_UNKNOWN ,  HP1SITEFACTOR_Q6 ,  VDR_Q6 ,  FXR_IR1_Q6 ,  AP1_Q6 ,  ZIC3_01 ,  CTTTGA_LEF1_Q2 ,  TGACCTY_ERR1_Q2 ,  TCF4_Q5 ,  HNF4_DR1_Q3 ,  WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  HNF4_01 ,  TATAAA_TATA_01 ,  AR_Q6 ,  LEF1_Q6 ,  GGGGCCC_MIR296 ,  GGATTA_PITX2_Q2 ,  CDX2_Q5 ,  CAGGTG_E12_Q6 ,  DR1_Q3 ,  PXR_Q2 ,  TST1_01 ,  WYAAANNRNNNGCG_UNKNOWN ,  RRAGTTGT_UNKNOWN ,  RAAGNYNNCTTY_UNKNOWN ,  AP1_Q4 ,  YCATTAA_UNKNOWN ,  NCX_01 ,  EN1_01 ,  TTGTTT_FOXO4_01 ,  CAAGGAT_MIR362 ,  PIT1_Q6 ,  GATA4_Q3 ,  MSX1_01 ,  RTTTNNNYTGGM_UNKNOWN ,  COUP_DR1_Q6 ,  PAX_Q6 ,  TGATTTRY_GFI1_01 ,  CTTTGT_LEF1_Q2 ,  CAGCTG_AP4_Q5 ,  AACTTT_UNKNOWN ,  PPAR_DR1_Q2 ,  HNF4_01_B

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-362 ,  Predicted Gene Targets for miR-375

Cytogenetic Map:

2q31.1

search → result