QuickView for Hsc70-interacting protein (gene)

Gene Symbol:

ST13 Homo sapiens

Full name:

ST13, Hsp70 interacting protein

Synonyms:

AAG2, FAM10A1, FAM10A4, HIP, HOP, HSPABP, HSPABP1, P48, PRO0786, SNC6, hsc70-interacting protein, Hsp70-interacting protein, aging-associated protein 2, heat shock 70kD protein binding protein, progesterone receptor-associated p48 protein, putative tumor suppressor ST13, renal carcinoma antigen NY-REN-33, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein), suppression of tumorigenicity 13 protein, testis secretory sperm-binding protein Li 233m

Genomic Location:

Chr 22: 39550545-39582633

Description:

The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in...

View Full Description

The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  PR_02 ,  TTANTCA_UNKNOWN ,  CREBP1CJUN_01 ,  RYTTCCTG_ETS2_B ,  EFC_Q6 ,  TTCNRGNNNNTTC_HSF_Q6 ,  GGGACCA_MIR133A_MIR133B ,  GR_Q6_01 ,  RFX1_01 ,  TGAYRTCA_ATF3_Q6 ,  RGAANNTTC_HSF1_01 ,  ATF_01 ,  HSF1_01 ,  TTCYRGAA_UNKNOWN ,  CREB_02 ,  HSF_Q6 ,  HSF2_01 ,  RNGTGGGC_UNKNOWN ,  IK2_01 ,  CP2_02 ,  CTGCAGY_UNKNOWN ,  TGACGTCA_ATF3_Q6 ,  GRE_C ,  TGACATY_UNKNOWN ,  PPARA_02 ,  CREB_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-133

Cytogenetic Map:

22q13.2

search → result