QuickView for Hspa5 (gene)

Gene Symbol:

HSPA5 Homo sapiens

Full name:

heat shock protein family A (Hsp70) member 5

Synonyms:

BIP, GRP78, HEL-S-89n, MIF2, 78 kDa glucose-regulated protein, endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, epididymis secretory sperm binding protein Li 89n, glucose-regulated protein, 78kDa, heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), immunoglobulin heavy chain-binding protein

Genomic Location:

Chr 9: 127036953-127043430

Description:

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  GCANCTGNY_MYOD_Q6 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  GGGYGTGNY_UNKNOWN ,  GTTTGTT_MIR495 ,  GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  CAGCTG_AP4_Q5 ,  ACACTGG_MIR199A_MIR199B

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-199 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-379 ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-378

Cytogenetic Map:

9q33.3

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