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QuickView for IFNAR1 (gene)

Gene Symbol:
IFNAR1 Homo sapiens Homo sapiens
Full name:
interferon alpha and beta receptor subunit 1
AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha/beta receptor 1, CRF2-1, IFN-R-1, IFN-alpha/beta receptor 1, alpha-type antiviral protein, beta-type antiviral protein, cytokine receptor class-II member 1, cytokine receptor family 2 member 1, interferon (alpha, beta and omega) receptor 1, interferon receptor 1, interferon-alpha/beta receptor alpha chain, interferon-beta receptor 1, type I interferon receptor 1
Genomic Location:
Chr 21: 33619084-33653999
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 21

GO Molecular Function

cytokine binding | transmembrane signaling receptor activity | signaling receptor activity | type I interferon receptor activity | interferon receptor activity | cytokine receptor activity | protein binding | type I interferon binding

GO Biological Process

response to virus | response to cytokine | response to lipopolysaccharide | intracellular signal transduction | cellular response to type I interferon | cellular response to interferon-alpha | JAK-STAT cascade | defense response | cellular process | response to type I interferon | regulation of cellular process | response to stimulus | response to stress | response to molecule of bacterial origin | response to external biotic stimulus | response to lipid | cytokine-mediated signaling pathway | response to interferon-alpha | cellular response to cytokine stimulus | type I interferon receptor activity | interferon receptor activity | cytokine receptor activity | response to bacterium | cell communication | response to organic substance | cell surface receptor signaling pathway | immune response | type I interferon signaling pathway | signaling | response to biotic stimulus | innate immune response | immune system process | cellular response to organic substance | response to other organism | signal transduction

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | late endosome | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endomembrane system | plasma membrane | vacuole | vesicle | lytic vacuole | integral component of plasma membrane | endosome | membrane-bounded organelle | organelle | lysosome | cell periphery | intracellular vesicle | intracellular | membrane | intrinsic component of plasma membrane