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QuickView for IFNGR1 (gene)


Gene Symbol:
IFNGR1 Homo sapiens Homo sapiens
Full name:
interferon gamma receptor 1
Synonyms:
CD119, IFNGR, IMD27A, IMD27B, interferon gamma receptor 1, AVP, type 2, CD119 antigen, CDw119, IFN-gamma receptor 1, IFN-gamma-R-alpha, IFN-gamma-R1, antiviral protein, type 2, immune interferon receptor 1, interferon-gamma receptor alpha chain
Genomic Location:
Chr 6: 137560315-137582200
Description:
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 6
6q23.3





GO Molecular Function

cytokine binding | transmembrane signaling receptor activity | signaling receptor activity | interferon receptor activity | cytokine receptor activity | protein binding | interferon-gamma receptor activity

GO Biological Process

response to virus | response to cytokine | regulation of immune system process | defense response | regulation of response to interferon-gamma | cellular process | regulation of response to cytokine stimulus | regulation of immune response | regulation of cellular process | interferon-gamma-mediated signaling pathway | regulation of interferon-gamma-mediated signaling pathway | cellular response to interferon-gamma | response to stimulus | response to stress | response to external biotic stimulus | regulation of signal transduction | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | interferon receptor activity | cytokine receptor activity | cell communication | regulation of cytokine-mediated signaling pathway | response to organic substance | regulation of innate immune response | cell surface receptor signaling pathway | interferon-gamma receptor activity | immune response | response to interferon-gamma | regulation of cell communication | signaling | response to biotic stimulus | innate immune response | immune system process | cellular response to organic substance | response to other organism | signal transduction | regulation of signaling

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane