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QuickView for IFT140;jsessionid=C85A03747260F23886480186112F8732 (gene)


Gene Symbol:
IFT140 Homo sapiens Homo sapiens
Full name:
intraflagellar transport 140
Synonyms:
MZSDS, RP80, SRTD9, WDTC2, c305C8.4, c380F5.1, gs114, intraflagellar transport protein 140 homolog, WD and tetratricopeptide repeats protein 2, intraflagellar transport 140 homolog
Genomic Location:
Chr 16: 1500431-1597299
Description:
This gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the f...
Orthologs:
Mus musculus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Rattus norvegicus
External Links:
Entrez Gene
Cytogenetic Map:
chr 16
16p13.3





GO Molecular Function

protein binding

GO Biological Process

limb development | microtubule-based transport | cranial skeletal system development | embryonic brain development | eye development | establishment of localization | neural tube patterning | embryonic appendage morphogenesis | cell differentiation | nervous system development | neurogenesis | regulation of organelle organization | generation of neurons | intracellular transport | microtubule-based process | pattern specification process | cellular process | localization | limb morphogenesis | neuron development | determination of left/right symmetry | macromolecule localization | regulation of smoothened signaling pathway | establishment of localization in cell | tissue development | cytoskeleton-dependent intracellular transport | regulation of cellular process | epithelium development | cellular component organization | urogenital system development | embryonic limb morphogenesis | regulation of cilium assembly | photoreceptor cell outer segment organization | microtubule-based movement | cellular localization | embryonic skeletal system development | cellular component assembly | embryo development | organelle assembly | regulation of cell projection assembly | system development | regulation of signal transduction | multicellular organism development | determination of bilateral symmetry | cell projection assembly | animal organ morphogenesis | protein localization to organelle | embryonic camera-type eye development | neural tube development | sensory organ development | chordate embryonic development | skeletal system morphogenesis | intraciliary transport | protein-containing complex localization | heart development | embryo development ending in birth or egg hatching | renal system development | embryonic morphogenesis | intraciliary transport involved in cilium assembly | neuron differentiation | embryonic organ morphogenesis | embryonic cranial skeleton morphogenesis | intraciliary retrograde transport | regionalization | retina development in camera-type eye | anatomical structure development | embryonic skeletal system morphogenesis | cell projection organization | embryonic organ development | transport along microtubule | cellular protein localization | animal organ development | cilium assembly | camera-type eye development | cilium organization | regulation of cell communication | protein localization to cilium | cell development | embryonic digit morphogenesis | protein localization | anatomical structure morphogenesis | cellular macromolecule localization | developmental process | organelle organization | tube development | photoreceptor cell development | regulation of cell projection organization | skeletal system development | photoreceptor cell differentiation | regulation of organelle assembly | circulatory system development | non-motile cilium assembly | regulation of cellular component organization | regulation of signaling | multicellular organismal process

GO Cellular Component

ciliary transition zone | non-motile cilium | intraciliary transport particle A | neuron projection | microtubule organizing center | cell | cytoplasm | intracellular organelle | centrosome | protein-containing complex | cell projection | plasma membrane bounded cell projection cytoplasm | photoreceptor connecting cilium | cilium | photoreceptor outer segment | microtubule cytoskeleton | cytoplasmic region | axoneme | 9+0 non-motile cilium | photoreceptor cell cilium | organelle | ciliary plasm | intraciliary transport particle | cytoskeleton | ciliary tip | intracellular | ciliary basal body