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QuickView for IL13RA2 (gene)


Gene Symbol:
IL13RA2 Homo sapiens Homo sapiens
Full name:
interleukin 13 receptor subunit alpha 2
Synonyms:
CD213A2, CT19, IL-13R, IL13BP, interleukin-13 receptor subunit alpha-2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, IL-13R-alpha-2, IL-13RA2, cancer/testis antigen 19, interleukin 13 binding protein, interleukin 13 receptor alpha 2 chain, interleukin 13 receptor, alpha 2
Genomic Location:
Chr X: 114144794-114158463
Description:
The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Canis lupus familiaris Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr X
Xq23


Transcripts Names
NM_000640
Protein Names
O00667
A8K7E2
Q14627



GO Molecular Function

cytokine binding | transmembrane signaling receptor activity | signaling receptor activity | cytokine receptor activity | protein binding

GO Biological Process

negative regulation of leukocyte activation | adaptive immune response | negative regulation of intracellular transport | negative regulation of immune system process | response to cytokine | regulation of cellular localization | regulation of localization | regulation of immune system process | negative regulation of cellular process | cellular process | positive regulation of immune effector process | negative regulation of secretion | negative regulation of mast cell activation | regulation of immune response | regulation of cellular process | regulation of mast cell degranulation | response to stimulus | positive regulation of immune system process | negative regulation of transport | regulation of intracellular transport | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | negative regulation of immunoglobulin production | negative regulation of secretion by cell | leukocyte mediated immunity | regulation of mast cell activation | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | negative regulation of immune response | cytokine receptor activity | cell communication | negative regulation of cell activation | negative regulation of mast cell activation involved in immune response | negative regulation of exocytosis | response to organic substance | regulation of exocytosis | cell surface receptor signaling pathway | regulation of vesicle-mediated transport | regulation of secretion | immune response | regulation of cell activation | regulation of regulated secretory pathway | signaling | regulation of immunoglobulin production | B cell mediated immunity | regulation of transport | immunoglobulin mediated immune response | immune system process | cellular response to organic substance | negative regulation of mast cell degranulation | signal transduction

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | receptor complex | protein-containing complex | plasma membrane | extracellular region | extracellular space | cell periphery | cell surface | membrane