QuickView for INHBA;jsessionid=2B262788FB370241737E4905EF8968CA (gene)
- Gene Symbol:
- INHBA
Homo sapiens - Full name:
- inhibin beta A subunit
- Synonyms:
- EDF, FRP, inhibin beta A chain, FSH-releasing protein, Inhibin, beta-1, activin beta-A chain, erythroid differentiation factor, erythroid differentiation protein, follicle-stimulating hormone-releasing protein, inhibin, beta A (activin A, activin AB alpha polypeptide)
- Genomic Location:
- Chr 7: 41695126-41709231
- Description:
-
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
7p14.1
GO Molecular Function
peptide binding | peptide hormone binding | transforming growth factor beta receptor binding | signaling receptor binding | cytokine receptor binding | inhibin binding | hormone activity | receptor serine/threonine kinase binding | molecular function regulator | activin receptor binding | amide binding | identical protein binding | protein heterodimerization activity | type II activin receptor binding | hormone binding | protein binding | receptor regulator activity | protein dimerization activity | growth factor activity | receptor ligand activity | cytokine activity
GO Biological Process
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | negative regulation of lymphocyte differentiation | negative regulation of leukocyte activation | positive regulation of erythrocyte differentiation | negative regulation of phosphorylation | brain development | molting cycle | SMAD protein signal transduction | striatal medium spiny neuron differentiation | regulation of extrinsic apoptotic signaling pathway in absence of ligand | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | regulation of B cell activation | developmental process involved in reproduction | ovarian follicle development | positive regulation of apoptotic process | regulation of localization | subpallium development | gonad development | lipid transport | regulation of programmed cell death | hormone secretion | female gonad development | erythrocyte homeostasis | eye development | establishment of localization | regulation of immune system process | response to hormone | myeloid cell differentiation | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | defense response | nervous system development | response to drug | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | secretion | progesterone secretion | regulation of cytokine biosynthetic process | negative regulation of follicle-stimulating hormone secretion | localization | extrinsic apoptotic signaling pathway | mesoderm morphogenesis | odontogenesis | negative regulation of signaling | central nervous system neuron differentiation | reproductive system development | mesoderm development | positive regulation of pathway-restricted SMAD protein phosphorylation | immune system development | multicellular organismal reproductive process | macromolecule localization | negative regulation of secretion | regulation of cell cycle | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | forebrain neuron differentiation | negative regulation of hormone secretion | negative regulation of cellular metabolic process | tissue development | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | negative regulation of gonadotropin secretion | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | positive regulation of cellular protein metabolic process | epithelium development | development of primary sexual characteristics | head development | response to stimulus | positive regulation of immune system process | positive regulation of protein metabolic process | mesoderm formation | response to stress | negative regulation of lymphocyte activation | regulation of cell proliferation | ovulation cycle | activin receptor signaling pathway | roof of mouth development | negative regulation of interferon-gamma production | hematopoietic progenitor cell differentiation | programmed cell death | development of primary female sexual characteristics | reproduction | secretion by cell | response to alcohol | rhythmic process | positive regulation of hormone secretion | cell cycle G1/S phase transition | negative regulation of transport | cellular response to organic cyclic compound | hormone activity | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | negative regulation of hemopoiesis | cellular biosynthetic process | embryo development | cell-cell signaling | GABAergic neuron differentiation | molecular function regulator | regulation of lymphocyte differentiation | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | apoptotic process | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of secretion by cell | negative regulation of growth | negative regulation of phosphate metabolic process | multicellular organism development | regulation of MAPK cascade | response to follicle-stimulating hormone | cellular response to cholesterol | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | telencephalon development | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | positive regulation of secretion | organic substance transport | response to lipid | cell cycle | cellular response to gonadotropin stimulus | negative regulation of cytokine production | positive regulation of cellular metabolic process | cellular response to sterol | positive regulation of protein phosphorylation | negative regulation of interferon-gamma biosynthetic process | regulation of lymphocyte activation | eyelid development in camera-type eye | animal organ morphogenesis | negative regulation of myeloid cell differentiation | striatum development | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | response to cholesterol | hemoglobin biosynthetic process | regulation of transcription by RNA polymerase II | endoderm formation | negative regulation of B cell differentiation | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | luteinization | homeostasis of number of cells | biosynthetic process | regulation of cellular protein metabolic process | positive regulation of follicle-stimulating hormone secretion | epidermis development | regulation of apoptotic signaling pathway | skin development | mitotic cell cycle phase transition | sensory organ development | positive regulation of ovulation | ovulation cycle process | negative regulation of cytokine biosynthetic process | endocrine process | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | negative regulation of macrophage differentiation | negative regulation of cell activation | regulation of endocrine process | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | G1/S transition of mitotic cell cycle | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of transport | negative regulation of cell growth | apoptotic signaling pathway | embryonic morphogenesis | negative regulation of B cell activation | neuron differentiation | multicellular organism reproduction | regulation of signaling receptor activity | receptor regulator activity | development of primary male sexual characteristics | protein metabolic process | positive regulation of protein modification process | regulation of growth | hair cycle | response to organic substance | tissue morphogenesis | regulation of hemopoiesis | cell cycle arrest | male sex differentiation | response to wounding | regulation of intracellular signal transduction | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | growth factor activity | metabolic process | lipid localization | regulation of RNA biosynthetic process | male gonad development | regulation of erythrocyte differentiation | hair cycle process | forebrain generation of neurons | regulation of secretion | positive regulation of cell death | receptor ligand activity | hormone transport | cytokine activity | organic substance metabolic process | regulation of B cell differentiation | cell death | negative regulation of biosynthetic process | animal organ development | forebrain development | regulation of ovulation | regulation of cell activation | positive regulation of programmed cell death | skin epidermis development | regulation of phosphate metabolic process | response to gonadotropin | cellular response to follicle-stimulating hormone stimulus | drug transport | camera-type eye development | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of cell communication | regulation of macrophage differentiation | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | positive regulation of phosphorylation | regulation of follicle-stimulating hormone secretion | endodermal cell differentiation | regulation of cytokine production | endoderm development | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | reproductive structure development | regulation of developmental process | developmental process | erythrocyte differentiation | regulation of cell growth | regulation of transport | positive regulation of transcription, DNA-templated | hemoglobin metabolic process | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | signal release | cell cycle phase transition | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | central nervous system development | mesodermal cell differentiation | positive regulation of metabolic process | regulation of interferon-gamma production | gastrulation | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | negative regulation of myeloid leukocyte differentiation | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | hair follicle development | signal transduction | regulation of signaling | regulation of pathway-restricted SMAD protein phosphorylation | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
cell | inhibin A complex | activin A complex | cytoplasm | protein-containing complex | perinuclear region of cytoplasm | extracellular region | extracellular space | intracellular
