QuickView for ITPKB;jsessionid=F81EE8D8D9AD6886344715500552D246 (gene)

Gene Symbol:

ITPKB Homo sapiens

Full name:

inositol-trisphosphate 3-kinase B

Synonyms:

IP3-3KB, IP3K, IP3K-B, IP3KB, PIG37, inositol-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, inositol 1,4,5-trisphosphate 3-kinase B, insP 3-kinase B, proliferation-inducing protein 37

Genomic Location:

Chr 1: 224886014-224991818

Description:

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmoduli...

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The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

IRF1_01 ,  CMYB_01 ,  HNF3ALPHA_Q6 ,  PEA3_Q6 ,  MAF_Q6 ,  DBP_Q6 ,  TITF1_Q3 ,  CAGGTA_AREB6_01 ,  AR_01 ,  HNF3_Q6 ,  HNF3B_01 ,  NERF_Q2 ,  TGTTTGY_HNF3_Q6 ,  HFH8_01 ,  RNGTGGGC_UNKNOWN ,  ELK1_01 ,  GTTATAT_MIR410 ,  CDC5_01 ,  ETS1_B ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-142-3p ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-375 ,  Predicted Gene Targets for miR-410

Cytogenetic Map:

1q42.12

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