QuickView for Il10rb (gene)

Gene Symbol:

IL10RB Homo sapiens

Full name:

interleukin 10 receptor subunit beta

Synonyms:

CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2, interleukin-10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10RB, cytokine receptor class-II CRF2-4, cytokine receptor class-II member 4, cytokine receptor family 2 member 4, cytokine receptor family II, member 4, interleukin 10 receptor, beta, interleukin-10 receptor subunit 2

Genomic Location:

Chr 21: 33560542-33591390

Description:

The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form...

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The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

21q22.11

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