QuickView for Ind1 (gene)
- Gene Symbol:
- NUBPL
Homo sapiens - Full name:
- nucleotide binding protein like
- Synonyms:
- C14orf127, IND1, huInd1, iron-sulfur protein NUBPL, IND1 homolog, iron-sulfur protein required for NADH dehydrogenase
- Genomic Location:
- Chr 14: 31100342-31400181
- Description:
-
This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. Mutations in this gene cause mitochondrial complex I deficiency. Alternative splicing results ...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
14q12
GO Molecular Function
cofactor binding | cation binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | ATP binding | anion binding | adenyl nucleotide binding | iron-sulfur cluster binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | 4 iron, 4 sulfur cluster binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
sulfur compound metabolic process | cell part morphogenesis | cellular process | mitochondrial respiratory chain complex assembly | cellular component organization | mitochondrion morphogenesis | iron-sulfur cluster assembly | mitochondrial respiratory chain complex I assembly | cofactor metabolic process | cellular component assembly | mitochondrion organization | NADH dehydrogenase complex assembly | cellular protein-containing complex assembly | protein-containing complex assembly | anatomical structure development | metabolic process | anatomical structure morphogenesis | developmental process | organelle organization | cellular metabolic process
GO Cellular Component
mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | plasma membrane | mitochondrion | membrane-bounded organelle | organelle | cell periphery | membrane-enclosed lumen | intracellular | membrane
