QuickView for Interferon lambda-1 (gene)
- Gene Symbol:
- IFNL1
Homo sapiens - Full name:
- interferon lambda 1
- Synonyms:
- IL-29, IL29, interferon lambda-1, IFN-lambda-1, cytokine Zcyto21, interleukin 29 (interferon, lambda 1), interleukin-29
- Genomic Location:
- Chr 19: 44478805-44481152
- Description:
-
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral ...
- Orthologs:
- Macaca mulatta
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
19q13.2
GO Molecular Function
signaling receptor binding | cytokine receptor binding | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity | interleukin-28 receptor binding
GO Biological Process
positive regulation of immune response | negative regulation of lymphocyte differentiation | negative regulation of leukocyte activation | positive regulation of macromolecule biosynthetic process | response to virus | negative regulation of immune system process | response to cytokine | intracellular signal transduction | positive regulation of peptidyl-tyrosine phosphorylation | defense response to other organism | regulation of immune system process | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | negative regulation of RNA biosynthetic process | regulation of T cell differentiation | JAK-STAT cascade | defense response | positive regulation of phosphate metabolic process | positive regulation of cellular biosynthetic process | cellular process | regulation of MHC class I biosynthetic process | negative regulation of nucleic acid-templated transcription | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of immune response | regulation of cellular process | regulation of metabolic process | positive regulation of interferon-gamma production | regulation of type 2 immune response | positive regulation of cellular protein metabolic process | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | negative regulation of cell adhesion | response to stress | positive regulation of JAK-STAT cascade | negative regulation of lymphocyte activation | regulation of cell proliferation | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | negative regulation of hemopoiesis | regulation of cell adhesion | molecular function regulator | regulation of lymphocyte differentiation | regulation of nucleic acid-templated transcription | response to external biotic stimulus | regulation of signal transduction | regulation of phosphorylation | regulation of T cell activation | regulation of gene expression | negative regulation of cytokine production | positive regulation of cellular metabolic process | defense response to virus | positive regulation of protein phosphorylation | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | negative regulation of T cell activation | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | cellular response to cytokine stimulus | negative regulation of type 2 immune response | regulation of cellular protein metabolic process | negative regulation of immune response | negative regulation of memory T cell differentiation | negative regulation of cell-cell adhesion | cell communication | regulation of cellular metabolic process | positive regulation of tyrosine phosphorylation of STAT protein | negative regulation of cell activation | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of RNA metabolic process | negative regulation of interleukin-13 production | negative regulation of T cell differentiation | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | response to organic substance | regulation of hemopoiesis | regulation of JAK-STAT cascade | regulation of intracellular signal transduction | cell surface receptor signaling pathway | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | regulation of interleukin-5 production | receptor ligand activity | immune response | cytokine activity | negative regulation of biosynthetic process | negative regulation of gene expression | regulation of cell activation | regulation of phosphate metabolic process | positive regulation of cytokine production | regulation of cell communication | signaling | regulation of transcription, DNA-templated | positive regulation of phosphorylation | regulation of cytokine production | response to biotic stimulus | regulation of developmental process | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | regulation of cell-cell adhesion | innate immune response | positive regulation of nucleic acid-templated transcription | positive regulation of metabolic process | negative regulation of interleukin-5 production | regulation of interferon-gamma production | immune system process | cellular response to organic substance | positive regulation of MHC class I biosynthetic process | negative regulation of cell differentiation | regulation of memory T cell differentiation | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | cell | interleukin-28 receptor complex | plasma membrane protein complex | intrinsic component of membrane | receptor complex | protein-containing complex | plasma membrane | integral component of plasma membrane | extracellular region | extracellular space | cell periphery | intracellular | membrane | intrinsic component of plasma membrane
