QuickView for Interleukin 9 (gene)

Gene Symbol:

IL9 Homo sapiens

Full name:

interleukin 9

Synonyms:

HP40, IL-9, P40, interleukin-9, T-cell growth factor p40, cytokine P40, homolog of mouse T cell and mast cell growth factor 40, p40 T-cell and mast cell growth factor, p40 cytokine

Genomic Location:

Chr 5: 135255834-135259415

Description:

The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various ...

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The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  IRF1_01 ,  AP1_C ,  TGANTCA_AP1_C ,  AP1_Q6 ,  TGAYRTCA_ATF3_Q6 ,  RGAANNTTC_HSF1_01 ,  AP1_Q6_01 ,  AP1FJ_Q2 ,  TGCTGAY_UNKNOWN ,  AP1_Q2_01 ,  CTTTAAR_UNKNOWN ,  AP1_Q4 ,  AP1_Q2 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  STAT5A_02

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Cytogenetic Map:

5q31.1

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