Name: | Inulin |
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PubChem Compound ID: | 24763 |
Description: | A starch found in the tubers and roots of many plants. Since it is hydrolyzable to FRUCTOSE, it is classified as a fructosan. It has been used in physiologic investigation for determination of the rate of glomerular function. |
Molecular formula: | C228H382O191 |
Molecular weight: | 6179.36 g/mol |
Synonyms: |
EINECS 232-684-3; 189444-25-5; 9005-80-5; Inulin; AI3-19506; Inulin [BAN]
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Name: | Inulin |
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Name (isomeric): | DB00638 |
Drug Type: | small molecule |
Description: | A starch found in the tubers and roots of many plants. Since it is hydrolyzable to FRUCTOSE, it is classified as a fructosan. It has been used in physiologic investigation for determination of the rate of glomerular function. |
Brand: | Inulin USP 27, Inulin from Jerusalem artichokes |
Category: | Hypoglycemic Agents, Diagnostic Agents |
CAS number: | 9005-80-5 |
Indication: | Historically used in an important medical test of renal function, specifically a measure of glomerular filtration rate. Sometimes used to help relieve symptoms of diabetes mellitus - a condition characterised by hyperglycemia and/or hyperinsulinemia. |
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Pharmacology: |
The inulin test is a procedure by which the filtering capacity of the glomeruli (the main filtering structures of the kidney) is determined by measuring the rate at which inulin, the test substance, is cleared from blood plasma. Inulin is one of the more suitable and accurate substance to measure because it is a small, inert polysaccharide molecule...
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Mechanism of Action: |
As a diagnostic agent, inulin is readily soluble and essentially indigestible. It readily passes through the blood and into the urine. It is neither secreted nor resorbed by the kidney making it an excellent indicator for renal clearance rates. The inulin clearance test has largely been succeeded by the creatinine clearance test as a measure of glo...
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Absorption: | Poorly absorbed, passes through to urine unmetabolized |
Protein binding: | None |
Biotransformation: | Metabolized into carbon dioxide and methane by colonic bacteria |
Half Life: | 2-4 hours |
Affected organisms: | Humans and other mammals |