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QuickView for Isopropamide (compound)
PubChem
| Name: | isopropamide iodide |
|---|---|
| PubChem Compound ID: | 3775 |
| Molecular formula: | C23H33N2O+ |
| Molecular weight: | 353.521 g/mol |
| Synonyms: |
Isamid; Sanulcin; DivK1c_000240; Spectrum_000203; Tyrimide; Chloroisopropamide; NCGC00016308-01; C07055; Spectrum2_001051; NSC15548.
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DrugBank
Identification
| Name: | isopropamide iodide |
|---|---|
| Name (isomeric): | DB01625 |
| Drug Type: | small molecule |
| Synonyms: |
2,2-Diphenyl-4-diisopropylaminobutyramide methiodide; Isopropamide iodide; Isoproponum iodide; 4-(Diisopropylamino)-2,2-diphenylbutyramide methiodide; Chloroisopropamide
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| Brand: | Dipramide, Priazimide, Isamid, Darbid, Sanulcin, Piaccamide, Tyrimide, Priamide, Marygin-M, Dipramid |
| Category: | Gastrointestinal Agents |
| CAS number: | 7492-32-2 |
Pharmacology
| Indication: | For the treatment of a wide range of gastrointestinal disorders, including such conditions as peptic ulcer, gastritis, hyperchlorhydria, functional diarrhea, irritable or spastic colon, pyloroduodenal irritability, pylorospasm, acute nonspecific gastroenteritis, biliary dyskinesia and chronic cholelithiasis, duodenitis, gastrointestinal spasm; it may also be used to treat genitourinary spasm. |
|---|---|
| Pharmacology: | Isopropamide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility. |
| Mechanism of Action: |
Anticholinergics are a class of medications that inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movements of smooth muscles present in the gastrointestinal tract. Inhibi...
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| Toxicity: | Symptoms of overdose include dryness of mouth, dysphagia, thirst, blurred vision, dilated pupils, photophobia, fever, rapid pulse and respiration, disorientation. Depression and circulatory collapse may result from severe overdosage. |
| Affected organisms: | Humans and other mammals |
Interactions
| Drug interaction: |
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Targets
