QuickView for Itgb1 (gene)

Gene Symbol:

ITGB1 Homo sapiens

Full name:

integrin subunit beta 1

Synonyms:

CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB, integrin beta-1, glycoprotein IIa, integrin VLA-4 beta subunit, integrin beta 1, integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), very late activation protein, beta polypeptide

Genomic Location:

Chr 10: 33229326-33287204

Description:

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion...

View Full Description

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTGCCAT_MIR183 ,  RYTTCCTG_ETS2_B ,  ATGTACA_MIR493 ,  TAGCTTT_MIR9 ,  TEF1_Q6 ,  GGGCGGR_SP1_Q6 ,  GTGCCTT_MIR506 ,  WGGAATGY_TEF1_Q6 ,  TGGTGCT_MIR29A_MIR29B_MIR29C

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-134 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-223 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-493-5p

miRNA binding sites
(Source: miRecords):

hsa-miR-124 Targeted Genes

Cytogenetic Map:

10p11.22

search → result