QuickView for KCNH7 (gene)

Gene Symbol:

KCNH7 Homo sapiens

Full name:

potassium voltage-gated channel subfamily H member 7

Synonyms:

ERG3, HERG3, Kv11.3, potassium voltage-gated channel subfamily H member 7, ERG-3, eag-related protein 3, ether-a-go-go-related gene potassium channel 3, ether-a-go-go-related protein 3, potassium channel subunit HERG-3, potassium channel, voltage gated eag related subfamily H, member 7, voltage-gated potassium channel subunit Kv11.3

Genomic Location:

Chr 2: 162936163-163403486

Description:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume....

View Full Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  SMTTTTGT_UNKNOWN ,  GTACTGT_MIR101 ,  TACTTGA_MIR26A_MIR26B ,  STAT6_01 ,  TGACCTY_ERR1_Q2 ,  CDPCR3HD_01 ,  CEBP_Q2 ,  CACCCBINDINGFACTOR_Q6 ,  CAGGTG_E12_Q6 ,  CTCAGGG_MIR125B_MIR125A ,  CACCAGC_MIR138 ,  CAGCTTT_MIR320 ,  TST1_01 ,  AREB6_01 ,  STAT5A_03 ,  CEBPB_02 ,  CTTTAAR_UNKNOWN ,  HMGIY_Q6 ,  ATATGCA_MIR448 ,  GTGGGTGK_UNKNOWN ,  GGGTGGRR_PAX4_03

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-136 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-448

Cytogenetic Map:

2q24.2

search → result