QuickView for KCNMB3 (gene)

Gene Symbol:

KCNMB3 Homo sapiens

Full name:

potassium calcium-activated channel subfamily M regulatory beta subunit 3

Synonyms:

BKBETA3, HBETA3, K(VCA)BETA-3, KCNMB2, KCNMBL, SLO-BETA-3, SLOBETA3, calcium-activated potassium channel subunit beta-3, BK channel beta subunit 3, BK channel subunit beta-3, MaxiK channel beta-subunit 3, big potassium channel beta subunit 3, calcium-activated potassium channel regulatory subunit, calcium-activated potassium channel, subfamily M subunit beta-3, charybdotoxin receptor subunit beta-3, large conductance, voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit, maxi K channel subunit beta-3, potassium channel subfamily M regulatory beta subunit 3, potassium large conductance calcium-activated channel, subfamily M beta member 3

Genomic Location:

Chr 3: 180443246-180467532

Description:

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which m...

View Full Description

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGACCTY_ERR1_Q2 ,  HEB_Q6 ,  TATAAA_TATA_01 ,  ETS2_B ,  AP4_Q6_01 ,  ATF1_Q6 ,  GTCNYYATGR_UNKNOWN ,  RGAGGAARY_PU1_Q6 ,  ICSBP_Q6 ,  CAGCTG_AP4_Q5 ,  ELF1_Q6 ,  IRF2_01

View More

View Less

Cytogenetic Map:

3q26.32

search → result