QuickView for KCNMB4 (gene)

Gene Symbol:

KCNMB4 Homo sapiens

Full name:

potassium calcium-activated channel subfamily M regulatory beta subunit 4

Synonyms:

calcium-activated potassium channel subunit beta-4, BK channel beta subunit 4, BK channel subunit beta-4, BKbeta4, MaxiK channel beta-subunit 4, big potassium channel beta subunit 4, calcium-activated potassium channel, subfamily M subunit beta-4, charybdotoxin receptor subunit beta-4, hbeta4, k(VCA)beta-4, large conductance calcium-dependent potassium ion channel beta 4 subunit, maxi K channel subunit beta-4, potassium channel subfamily M regulatory beta subunit 4, potassium large conductance calcium-activated channel, subfamily M, beta member 4, slo-beta-4

Genomic Location:

Chr 12: 69046329-69111245

Description:

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which s...

View Full Description

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YTATTTTNR_MEF2_02

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-504

Cytogenetic Map:

12q15

search → result