QuickView for Kpna4 (gene)

Gene Symbol:

KPNA4 Homo sapiens

Full name:

karyopherin subunit alpha 4

Synonyms:

IPOA3, QIP1, SRP3, importin subunit alpha-3, importin alpha Q1, importin subunit alpha-4, karyopherin alpha 4 (importin alpha 3)

Genomic Location:

Chr 3: 161700656-161766070

Description:

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-...

View Full Description

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  ACTGTAG_MIR139 ,  TTTGCAC_MIR19A_MIR19B ,  AGCYRWTTC_UNKNOWN ,  TGANTCA_AP1_C ,  TTTGCAG_MIR518A2 ,  GATA1_01 ,  GCATTTG_MIR105 ,  TTTTGAG_MIR373 ,  CTTTGCA_MIR527 ,  ATGTACA_MIR493 ,  CTTTGTA_MIR524 ,  GTAGGCA_MIR189 ,  GGGYGTGNY_UNKNOWN ,  NFY_Q6_01 ,  ATACCTC_MIR202 ,  ZID_01 ,  GGGCGGR_SP1_Q6 ,  TAATAAT_MIR126 ,  GTGCCTT_MIR506 ,  TCTATGA_MIR376A_MIR376B ,  AATGTGA_MIR23A_MIR23B ,  TGACAGNY_MEIS1_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  CAATGCA_MIR33 ,  ACACTGG_MIR199A_MIR199B

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-189 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-190 ,  Predicted Gene Targets for miR-199 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-214 ,  Predicted Gene Targets for miR-217 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-224 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-33 ,  Predicted Gene Targets for miR-346 ,  Predicted Gene Targets for miR-361 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-376 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-155 ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-384 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-505 ,  Predicted Gene Targets for miR-543 ,  Predicted Gene Targets for miR-544 ,  Predicted Gene Targets for miR-378

View More

View Less

Cytogenetic Map:

3q25.33

search → result