QuickView for Ku70 (gene)
- Gene Symbol:
- Xrcc6
Mus musculus - Full name:
- X-ray repair complementing defective repair in Chinese hamster cells 6
- Synonyms:
- 70kDa, G22p1, Ku70, X-ray repair cross-complementing protein 6, 5'-dRP/AP lyase Ku70, 5'-deoxyribose-5-phosphate lyase Ku70, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Ku p70, ku autoantigen protein p70 homolog, thyroid autoantigen 70 kDa
- Genomic Location:
- Chr 15: 81846799-81870521
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
GATA1_01 , ZID_01 , USF_Q6 , SP1_Q6 , SREBP1_02 , AP2_Q3 , CREB_Q2_01 , HNF4_Q6 , YRTCANNRCGC_UNKNOWN , CTTTGA_LEF1_Q2
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | cyclin binding | nucleic acid binding | protein-containing complex binding | ribonucleotide binding | ATP-dependent DNA helicase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | lyase activity | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | damaged DNA binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | double-stranded telomeric DNA binding | purine ribonucleoside triphosphate binding | DNA helicase activity | protein binding | double-stranded DNA binding | hydrolase activity, acting on acid anhydrides | 5'-deoxyribose-5-phosphate lyase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | helicase activity | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | telomeric DNA binding | protein C-terminus binding | small molecule binding
GO Biological Process
positive regulation of immune response | RNA metabolic process | double-strand break repair | response to radiation | cellular response to X-ray | positive regulation of macromolecule biosynthetic process | telomere maintenance | protein heterotetramerization | hyperosmotic response | regulation of neurogenesis | regulation of cell development | response to X-ray | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | defense response | nervous system development | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | immune system development | negative regulation of nucleic acid-templated transcription | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cell differentiation | DNA geometric change | anatomical structure homeostasis | cellular hyperosmotic salinity response | regulation of immune response | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | ATP-dependent DNA helicase activity | response to stimulus | positive regulation of innate immune response | positive regulation of immune system process | positive regulation of protein metabolic process | response to salt stress | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | activation of innate immune response | cellular nitrogen compound metabolic process | telomere organization | double-strand break repair via nonhomologous end joining | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | DNA recombination | DNA repair | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | multicellular organism development | cellular response to DNA damage stimulus | protein complex oligomerization | regulation of catalytic activity | regulation of phosphorylation | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular response to radiation | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | cellular response to gamma radiation | positive regulation of cell differentiation | V(D)J recombination | biosynthetic process | response to osmotic stress | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | protein tetramerization | double-strand break repair via classical nonhomologous end joining | response to gamma radiation | DNA duplex unwinding | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | homeostatic process | regulation of protein phosphorylation | regulation of RNA metabolic process | cellular hyperosmotic response | DNA helicase activity | positive regulation of molecular function | protein-containing complex assembly | activation of immune response | positive regulation of protein modification process | regulation of innate immune response | regulation of kinase activity | DNA metabolic process | cellular response to osmotic stress | anatomical structure development | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | positive regulation of kinase activity | cellular response to ionizing radiation | cellular response to salt stress | regulation of phosphate metabolic process | transcription, DNA-templated | hyperosmotic salinity response | regulation of transcription, DNA-templated | positive regulation of phosphorylation | protein heterooligomerization | somatic cell DNA recombination | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | developmental process | organelle organization | positive regulation of transcription, DNA-templated | innate immune response | positive regulation of nucleic acid-templated transcription | DNA conformation change | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | immune system process | cellular metabolic process | regulation of smooth muscle cell proliferation | response to ionizing radiation | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | DNA repair complex | cell | nuclear lumen | transcription factor complex | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nonhomologous end joining complex | protein-DNA complex | nucleoplasm | nuclear chromosome | chromosome, telomeric region | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | Ku70:Ku80 complex | nuclear chromosome, telomeric region | intracellular
