QuickView for LALBA (gene)

Gene Symbol:

LALBA Homo sapiens

Full name:

lactalbumin alpha

Synonyms:

LYZG, alpha-lactalbumin, lactose synthase B protein, lysozyme G, lysozyme-like protein 7

Genomic Location:

Chr 12: 47247734-47250096

Description:

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, al...

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This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT6_02 ,  PEA3_Q6 ,  SRY_01 ,  MAF_Q6 ,  TTGTTT_FOXO4_01 ,  CTTTGT_LEF1_Q2

Cytogenetic Map:

12q13.11

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